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Relion external MicAssess job support

These scripts can be called inside the Relion user interface in the External jobs section. They setup a correct Relion directory structure and call the external MicAssess program to assess the quality of K3 movies. After the micrograph assessment the scripts generate a Relion star file with good micrographs to continue with the CTF job step but also a filelist for cleanup of maybe not-good movies.

MicAssess can handle float32 and float16 micrographs.

These scripts have been tested with Relion 3.1 and 4.0beta2 and MicAssess 1.0.

Known limitations

  • All MRC files in Relion are organized in a Movies or Micrographs folder. The user guide provides examples how to link movies from a complex EPU folder into this structure.

Installation

It is assumed that the Relion and MicAssess software is already installed and the pre-trained model files are downloaded from the original site.

  1. Checkout the repository or download the bash scripts

  2. Decide if you run the scripts locally on a workstation or submit the MicAssess job to a computing cluster. A working example from our SLURM cluster is provided.

  3. Adapt and add the settings from env.source file to your environment (e.g. $HOME/.bashrc). Alternatively you can adapt and copy the file env.modules to e.g. $HOME/privatemodules/relion-ext-micassess if you are using environment modules.

  4. Put the bash script relion_ext_micassess.sh to $PATH like /usr/local/bin or choose it via the Browse button in Relion.

User guide

A simple user guide can be found on Relion MicAssess integration

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Relion external MicAssess integration

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