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HypertranSynergy

A Granularity-level Information Fusion Strategy on Hypergraph Transformer for Predicting Synergistic Effects of Anticancer Drugs

HypertranSynergy is a hypergraph learning network model used to predict the synergistic effect of anticancer drugs. It mainly includes two parts: CIE is a coarse-grained information extraction module based on hypergraph transformer, and FIE is a fine-grained information extraction module based on attention network. By coupling the two parts into HypertranSynergy, you can make the embeddings contain rich grain-level information to make prediction.

Requirements

  • Python 3.7 or higher
  • PyTorch 1.8.0 or higher
  • deepchem 2.5.0
  • rdkit 2022.9.5
  • torch-geometric 2.1.0

Running the Code

  • Running the "main_.py" for the classification task.
  • Running the "main_reg.py" for the regression task.

Acknowledgement

Thanks the code from Hts

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