This is an (incomplete) alphabetic list of projects that use Sphinx or are experimenting with using it for their documentation. If you like to be included, please mail to the Google group.
I've grouped the list into sections to make it easier to find interesting examples.
- Alabaster
- Blinker
- Calibre
- CherryPy
- Click (customized)
- coala (customized)
- CodePy
- Django Q
- Eve (Python REST API framework)
- Fabric
- Fityk
- Flask
- Flask-OpenID
- Invoke
- Jinja
- Lino (customized)
- marbl
- MeshPy
- Molecule
- Momotor LTI
- Podman
- PyCUDA
- PyOpenCL
- PyLangAcq
- pytest (customized)
- python-apt
- PyVisfile
- Requests
- searx
- Spyder (customized)
- Tablib
- urllib3 (customized)
- Werkzeug
- Write the Docs
- Advanced Generic Widgets (customized)
- Apache CouchDB (customized)
- APSW
- Arb
- Beautiful Soup
- Blender API
- Bugzilla
- Buildbot
- CMake (customized)
- Chaco (customized)
- Cormoran
- DEAP (customized)
- Director
- EZ-Draw (customized)
- Generic Mapping Tools (GMT) (customized)
- Genomedata
- GetFEM (customized)
- Glasgow Haskell Compiler (customized)
- Grok (customized)
- GROMACS
- GSL Shell
- Hands-on Python Tutorial
- Kaa (customized)
- Leo (customized)
- Mayavi (customized)
- MediaGoblin (customized)
- mpmath
- OpenCV (customized)
- OpenEXR
- OpenGDA
- phpDocumentor (customized)
- Plone (customized)
- PyEMD
- Pyevolve
- Pygame (customized)
- PyMQI
- PyQt4 (customized)
- PyQt5 (customized)
- Python 2
- Python 3 (customized)
- Python Packaging Authority (customized)
- Ring programming language (customized)
- SageMath (customized)
- Segway
- simuPOP (customized)
- SymPy
- TurboGears (customized)
- tvtk
- Varnish (customized, alabaster for index)
- Waf
- wxPython Phoenix (customized)
- z3c
- zc.async (customized)
- Zope (customized)
- ABRT
- cartopy
- Jython
- LLVM
- PyCantonese
- Pyre
- pySPACE
- Pysparse
- PyTango
- Python Wild Magic (customized)
- RDKit
- Reteisi (customized)
- Sqlkit (customized)
- Turbulenz
- Alembic
- Cython
- easybuild
- libLAS (customized)
- Lmod
- MapServer (customized)
- PyWavelets
- Setuptools
- Spring Python
- StatsModels (customized)
- Sylli
- Breathe (haiku)
- Breezy (fork of Bazaar) (agogo)
- MPipe (sphinx13)
- NLTK (agogo)
- PyPubSub (bizstyle)
- Pylons (pyramid)
- Pyramid web framework (pyramid)
- RxDock (bizstyle)
- Sphinx (sphinx13) :-)
- Valence (haiku, customized)
- Aesara (fork of Theano)
- Annotator
- Ansible (customized)
- Arcade
- aria2
- ASE
- asvin
- Autofac
- BigchainDB
- Blender Reference Manual
- Blocks
- bootstrap-datepicker
- Certbot
- CKAN
- Copr Buildsystem (customized)
- Coreboot
- Chainer (customized)
- citeproc-js
- cloud-init
- CodeIgniter
- Conda
- Corda
- Dask
- Databricks (customized)
- Dataiku DSS
- DNF
- Distro Tracker
- Django-cas-ng
- dj-stripe
- edX
- Electrum
- Elemental
- ESWP3
- Ethereum Homestead
- Exhale
- Faker
- Fidimag
- Flake8
- Flatpak
- FluidDyn
- Fluidsim
- Gallium
- GeoNode
- Glances
- Godot
- Graylog
- GPAW (customized)
- HDF5 for Python (h5py)
- HyperKitty
- Hyperledger Fabric
- Hyperledger Sawtooth
- IdentityServer
- Idris
- Inkscape (customized)
- javasphinx
- Jupyter Notebook
- Kanboard
- Lasagne
- latexindent.pl
- Learning Apache Spark with Python
- LibCEED
- Linguistica
- Linux kernel
- Mailman
- MathJax
- MDTraj (customized)
- Mesa 3D
- micca - MICrobial Community Analysis
- MicroPython
- Mink
- Mockery
- mod_wsgi
- MoinMoin
- Mopidy
- mpi4py
- MyHDL
- Mypy
- Netgate Docs
- Nextcloud Server
- Nextflow
- nghttp2
- NICOS (customized)
- OpenFAST
- Panda3D (customized)
- Pelican
- picamera
- Pillow
- pip
- Paver
- peewee
- Phinx
- phpMyAdmin
- PHPUnit
- PHPWord
- PROS (customized)
- Pweave
- pyca/cryptograhpy
- pyglet
- PyNaCl
- pyOpenSSL
- PyPy
- python-sqlparse
- PyVISA
- Read The Docs
- RenderDoc
- ROCm Platform
- Free your information from their silos (French) (customized)
- Releases Sphinx extension
- Qtile
- Quex
- QuTiP
- Scapy
- SimGrid
- SimPy
- six
- Solidity
- Sonos Controller (SoCo)
- Sphinx AutoAPI
- sphinx-argparse
- sphinx-tabs
- Sphinx-Gallery (customized)
- Sphinx with Github Webpages
- SpotBugs
- StarUML
- Sublime Text Unofficial Documentation
- SunPy
- Sylius
- Syncthing
- Tango Controls (customized)
- ThreatConnect
- TrueNAS (customized)
- Tuleap
- TYPO3 (customized)
- Veyon
- Ubiquity
- uWSGI
- virtualenv
- Wagtail
- Web Application Attack and Audit Framework (w3af)
- Weblate
- x265
- Zeek
- Zulip
- Bootstrap Theme
- C/C++ Software Development with Eclipse
- Dataverse
- e-cidadania
- Hangfire
- Hedge
- ObsPy
- OPNFV
- Pootle
- PyUblas
- seaborn
- Arviz
- Binder
- Bokeh
- CuPy
- EnOSlib
- Fairlearn
- Feature-engine
- Jupyter
- Jupyter Book
- Matplotlib
- MegEngine
- MNE-Python
- NetworkX
- Numpy
- Pandas
- Pystra (continuation of PyRe)
- PyVista
- SciPy
- SEPAL
- AIOHTTP
- Apache Cassandra
- Astropy
- Boto 3
- CakePHP
- Ceph
- Chef
- CKAN
- Confluent Platform
- Django
- django CMS
- Doctrine
- Enterprise Toolkit for Acrobat products
- FreeFEM
- fmt
- Gameduino
- gensim
- GeoServer
- gevent
- GHC - Glasgow Haskell Compiler
- Guzzle
- H2O.ai
- Heka
- Istihza (Turkish Python documentation project)
- JupyterHub
- Kombu
- Lasso
- Mako
- MirrorBrain
- Mitiq
- MongoDB
- Music21
- MyHDL
- ndnSIM
- nose
- ns-3
- ObjectListView
- OpenERP
- OpenCV
- Open Dylan
- OpenTURNS
- Open vSwitch
- PlatformIO
- Psycopg
- PyEphem
- Pygments
- Plone User Manual (German)
- PSI4
- PyMOTW
- python-aspectlib (sphinx_py3doc_enhanced_theme)
- QGIS
- Roundup
- SaltStack
- scikit-learn
- Scrapy
- Seaborn
- Selenium
- Self
- Substance D
- Sulu
- SQLAlchemy
- tinyTiM
- Twisted
- Ubuntu Packaging Guide
- WTForms
- Alan Crosswell's Using the Django REST Framework and DRF-JSONAPI
- Arizona State University PHY494/PHY598/CHM598 Simulation approaches to Bio-and Nanophysics (classic)
- Benoit Boissinot (classic, customized)
- EBI Cloud Consultancy Team (sphinx_rtd_theme)
- Eric Holscher (alabaster)
- Florian Diesch
- Institute for the Design of Advanced Energy Systems (IDAES) (sphinx_rtd_theme)
- IDAES Examples (sphinx_rtd_theme)
- Lei Ma's Statistical Mechanics lecture notes (sphinx_bootstrap_theme)
- Loyola University Chicago CS Academic Programs (sphinx_rtd_theme, customized)
- PyXLL (sphinx_bootstrap_theme, customized)
- SciPy Cookbook (sphinx_rtd_theme)
- Tech writer at work blog (custom theme)
- Thomas Cokelaer's Python, Sphinx and reStructuredText tutorials (standard)
- UC Berkeley ME233 Advanced Control Systems II course (sphinxdoc)
- Željko Svedružić's Biomolecular Structure and Function Laboratory (BioSFLab) (sphinx_bootstrap_theme)
- "The Art of Community" (Japanese translation)
- "Die Wahrheit des Sehens. Der DEKALOG von Krzysztof Kieślowski"
- "Expert Python Programming"
- "Expert Python Programming" (Japanese translation)
- "Expert Python Programming 2nd Edition" (Japanese translation)
- "The Hitchhiker's Guide to Python"
- "LassoGuide"
- "Learning Sphinx" (in Japanese)
- "Learning System Programming with Go (Japanese)"
- "Mercurial: the definitive guide (Second edition)"
- "Mithril -- The fastest clientside MVC (Japanese)"
- "Pioneers and Prominent Men of Utah"
- "Pomodoro Technique Illustrated" (Japanese translation)
- "Professional Software Development"
- "Python Professional Programming" (in Japanese)
- "Python Professional Programming 2nd Edition" (in Japanese)
- "Python Professional Programming 3rd Edition" (in Japanese)
- Python Course by Yuri Petrov (Russian)
- "Real World HTTP -- Learning The Internet and Web Technology via its history and code (Japanese)"
- "Redmine Primer 5th Edition (in Japanese)"
- "The repoze.bfg Web Application Framework"
- "The Self-Taught Programmer" (Japanese translation)
- "Simple and Steady Way of Learning for Software Engineering" (in Japanese)
- "Software-Dokumentation mit Sphinx"
- "Theoretical Physics Reference"
- "The Varnish Book"
- Read the Docs, a software-as-a-service documentation hosting platform, uses Sphinx to automatically build documentation updates that are pushed to GitHub.
- Spyder, the Scientific Python Development Environment, uses Sphinx in its help pane to render rich documentation for functions, classes and methods automatically or on-demand.