From db4a20792d93822fb12f8577c8a0bc84d1d4ffb8 Mon Sep 17 00:00:00 2001 From: bvarner-ebi <95643797+bvarner-ebi@users.noreply.github.com> Date: Wed, 23 Aug 2023 14:42:20 +0100 Subject: [PATCH] Addresses #2122 Refresh imports 08-2023 --- src/ontology/imports/merged_import.owl | 2509 +++++++++++++++++++++++- src/patterns/definitions.owl | 4 +- 2 files changed, 2464 insertions(+), 49 deletions(-) diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl index 678d15d9f..cb6a754f7 100644 --- a/src/ontology/imports/merged_import.owl +++ b/src/ontology/imports/merged_import.owl @@ -7,8 +7,8 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-08-09") + +Annotation(owl:versionInfo "2023-08-23") Declaration(Class()) Declaration(Class()) @@ -137,6 +137,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -714,6 +715,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -741,6 +743,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -864,6 +867,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -888,6 +894,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1284,6 +1294,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1472,6 +1483,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1524,6 +1536,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1568,6 +1581,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1594,6 +1609,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1644,6 +1661,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1733,6 +1751,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2089,6 +2109,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2229,6 +2250,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2288,6 +2310,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2341,6 +2364,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2582,6 +2606,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2751,6 +2776,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2853,6 +2879,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2864,6 +2891,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2880,6 +2908,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2943,6 +2972,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3075,6 +3105,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3217,6 +3250,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3306,6 +3343,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3407,6 +3446,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3516,6 +3556,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3632,6 +3675,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3802,8 +3846,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3823,6 +3869,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3854,7 +3901,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4173,6 +4223,18 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4639,16 +4701,21 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4665,6 +4732,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4690,6 +4763,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4702,6 +4776,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4711,6 +4788,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4730,10 +4811,16 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5248,6 +5335,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5381,6 +5469,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5431,6 +5520,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5548,6 +5638,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5589,6 +5681,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5905,10 +5998,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5955,7 +6050,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5984,6 +6082,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6027,11 +6126,14 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6102,6 +6204,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6123,6 +6226,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6145,11 +6250,17 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6208,7 +6319,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6250,6 +6364,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6278,6 +6396,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6389,7 +6509,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6408,6 +6531,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6424,6 +6548,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6521,6 +6646,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6529,6 +6657,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6551,6 +6682,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6582,6 +6714,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6654,6 +6787,13 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6923,6 +7063,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6944,6 +7087,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6973,6 +7118,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6986,6 +7132,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7088,6 +7237,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7124,6 +7276,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7158,6 +7313,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7345,6 +7503,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7381,6 +7541,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7393,6 +7556,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7401,6 +7565,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7413,6 +7580,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7675,6 +7844,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11280,6 +11452,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -13562,7 +13735,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -13756,7 +13928,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -13786,7 +13957,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -13959,7 +14129,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -14739,7 +14908,7 @@ AnnotationAssertion( "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."@en) AnnotationAssertion( "is preceded by"@en) AnnotationAssertion( "preceded_by"@en) -AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:preceded_by") +AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:preceded_by") AnnotationAssertion( "BFO:0000062") AnnotationAssertion( "external") AnnotationAssertion( "uberon") @@ -15080,7 +15249,7 @@ AnnotationAssertion( "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en) AnnotationAssertion( "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."@en) AnnotationAssertion( "has_participant"@en) -AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:has_participant") +AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:has_participant") AnnotationAssertion( "RO:0000057") AnnotationAssertion( "external") AnnotationAssertion( "has_participant") @@ -15223,34 +15392,17 @@ AnnotationAssertion(rdfs:label "loca InverseObjectProperties( ) TransitiveObjectProperty() -# Object Property: (contained in) - -AnnotationAssertion( "contained in"@en) -AnnotationAssertion( "Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):"@en) -AnnotationAssertion( "Intended meaning: -domain: material entity -range: spatial region or site (immaterial continuant) - "@en) -AnnotationAssertion( "Containment is location not involving parthood, and arises only where some immaterial continuant is involved.") -AnnotationAssertion( "contained_in"@en) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "contained in"@en) -InverseObjectProperties( ) -ObjectPropertyDomain( ) -ObjectPropertyRange( ) - # Object Property: (contains) AnnotationAssertion( "contains"@en) -AnnotationAssertion( ) AnnotationAssertion( "RO:0001019") AnnotationAssertion( "uberon") AnnotationAssertion( "contains") -AnnotationAssertion( ) AnnotationAssertion( "contains") -AnnotationAssertion(rdfs:label "contains"@en) AnnotationAssertion(rdfs:label "contains") +AnnotationAssertion(rdfs:label "obsolete contains") +AnnotationAssertion(rdfs:seeAlso ) +AnnotationAssertion(owl:deprecated "true"^^xsd:boolean) # Object Property: (located in) @@ -15262,7 +15414,7 @@ AnnotationAssertion( "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en) AnnotationAssertion( "located_in"@en) AnnotationAssertion( ) -AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:located_in") +AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:located_in") AnnotationAssertion( "RO:0001025") AnnotationAssertion( "uberon") AnnotationAssertion( "located_in") @@ -17950,12 +18102,6 @@ AnnotationAssertion( "process has causal agent") SubObjectPropertyOf( ) -# Object Property: (correlated with) - -AnnotationAssertion( "A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.") -AnnotationAssertion( "Groups both positive and negative correlation") -AnnotationAssertion(rdfs:label "correlated with") - # Object Property: (directly positively regulates) AnnotationAssertion( "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.") @@ -18278,20 +18424,10 @@ AnnotationAssertion( ) AnnotationAssertion( "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.") AnnotationAssertion( "See github ticket https://github.com/oborel/obo-relations/issues/497") -AnnotationAssertion( "2021-11-08T12:00:00Z") +AnnotationAssertion( "2021-11-08T12:00:00Z"^^xsd:dateTime) AnnotationAssertion( "utilizes") AnnotationAssertion(rdfs:label "device utilizes material"@en) -# Object Property: (positively correlated with) - -AnnotationAssertion( "A relation between entities in which one increases or decreases as the other does the same."@en) -AnnotationAssertion( "directly correlated with"@en) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positively correlated with"@en) -SubObjectPropertyOf( ) -SymmetricObjectProperty() -ReflexiveObjectProperty() - # Object Property: (regulates characteristic) AnnotationAssertion( "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.") @@ -19338,6 +19474,20 @@ AnnotationAssertion(rdfs:label "ossi EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (neurotransmitter uptake) + +AnnotationAssertion(Annotation( "ISBN:0123668387") "The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.") +AnnotationAssertion( "neurotransmitter recycling") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurotransmitter import") +AnnotationAssertion( "neurotransmitter import into glial cell") +AnnotationAssertion( "neurotransmitter import into neuron") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001504") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neurotransmitter uptake") +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of neurotransmitter levels) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates levels of neurotransmitter.") @@ -19647,6 +19797,20 @@ AnnotationAssertion( "G protein-coupled receptor binding") SubClassOf( ) +# Class: (response to hypoxia) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.") +AnnotationAssertion( "response to hypoxic stress") +AnnotationAssertion( "response to lowered oxygen tension") +AnnotationAssertion( "response to intermittent hypoxia") +AnnotationAssertion( "response to sustained hypoxia") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001666") +AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.") +AnnotationAssertion(rdfs:label "response to hypoxia") +SubClassOf( ) +SubClassOf( ) + # Class: (ameboidal-type cell migration) AnnotationAssertion(Annotation( "GOC:dph") "Cell migration that is accomplished by extension and retraction of a pseudopodium.") @@ -21216,6 +21380,74 @@ AnnotationAssertion( "regulation of heart rate") SubClassOf( ) +# Class: (regulation of L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:34:08Z") +AnnotationAssertion( "GO:1900920") +AnnotationAssertion( "regulation of L-glutamate import") +AnnotationAssertion( "regulation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of L-glutamate uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002036") +AnnotationAssertion(rdfs:label "regulation of L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:34:30Z") +AnnotationAssertion( "GO:1900921") +AnnotationAssertion( "down regulation of L-glutamate transport") +AnnotationAssertion( "down-regulation of L-glutamate transport") +AnnotationAssertion( "downregulation of L-glutamate transport") +AnnotationAssertion( "negative regulation of L-glutamate import") +AnnotationAssertion( "negative regulation of L-glutamate transport") +AnnotationAssertion( "regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of L-glutamate import") +AnnotationAssertion( "inhibition of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of L-glutamate uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of L-glutamate uptake") +AnnotationAssertion( "GO:0002037") +AnnotationAssertion(rdfs:label "negative regulation of L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:34:38Z") +AnnotationAssertion( "GO:1900922") +AnnotationAssertion( "positive regulation of L-glutamate import") +AnnotationAssertion( "positive regulation of L-glutamate transport") +AnnotationAssertion( "up regulation of L-glutamate transport") +AnnotationAssertion( "upregulation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of L-glutamate import") +AnnotationAssertion( "up-regulation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of L-glutamate import") +AnnotationAssertion( "activation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of L-glutamate uptake") +AnnotationAssertion( "stimulation of L-glutamate transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of L-glutamate uptake") +AnnotationAssertion( "GO:0002038") +AnnotationAssertion(rdfs:label "positive regulation of L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of neuroblast proliferation) AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the rate of neuroblast proliferation.") @@ -21480,6 +21712,55 @@ AnnotationAssertion(rdfs:label "male EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:11:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002181") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.") +AnnotationAssertion(rdfs:label "cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translational elongation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:14:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002182") +AnnotationAssertion(rdfs:label "cytoplasmic translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translational initiation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:15:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002183") +AnnotationAssertion(rdfs:label "cytoplasmic translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translational termination) + +AnnotationAssertion(Annotation( "GOC:hjd") "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:17:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002184") +AnnotationAssertion(rdfs:label "cytoplasmic translational termination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (somatic diversification of immune receptors) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") Annotation( "PMID:16166509") "The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.") @@ -26164,6 +26445,15 @@ AnnotationAssertion( "vascular process in circulatory system") SubClassOf( ) +# Class: (detection of oxygen) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003032") +AnnotationAssertion(rdfs:label "detection of oxygen") +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of systemic arterial blood pressure mediated by a chemical signal) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.") @@ -28967,6 +29257,15 @@ AnnotationAssertion(rdfs:label "mono EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (intracellular ligand-gated monoatomic ion channel activity) + +AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.") +AnnotationAssertion( "intracellular ligand-gated ion channel activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0005217") +AnnotationAssertion(rdfs:label "intracellular ligand-gated monoatomic ion channel activity") +SubClassOf( ) + # Class: (calcium activated cation channel activity) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_transport") "Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.") @@ -29500,7 +29799,9 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) DisjointClasses( ) +DisjointClasses( ) DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) # Class: (nuclear envelope) @@ -29712,6 +30013,26 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "Golgi-associated vesicle") SubClassOf( ) +# Class: (cytosol) + +AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "GOC:jl") "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.") +AnnotationAssertion( "NIF_Subcellular:sao101633890") +AnnotationAssertion( "Wikipedia:Cytosol") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005829") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytosol") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + # Class: (ribosome) AnnotationAssertion(Annotation( "ISBN:0198506732") "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.") @@ -30414,6 +30735,29 @@ AnnotationAssertion( "RNA localization") SubClassOf( ) +# Class: (RNA import into nucleus) + +AnnotationAssertion(Annotation( "GOC:ma") "The import of RNA from the cytoplasm to the nucleus.") +AnnotationAssertion( "RNA import into cell nucleus") +AnnotationAssertion( "RNA transport from cytoplasm to nucleus") +AnnotationAssertion( "RNA-nucleus import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006404") +AnnotationAssertion(rdfs:label "RNA import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (RNA export from nucleus) + +AnnotationAssertion(Annotation( "GOC:ma") "The directed movement of RNA from the nucleus to the cytoplasm.") +AnnotationAssertion( "RNA export from cell nucleus") +AnnotationAssertion( "RNA export out of nucleus") +AnnotationAssertion( "RNA transport from nucleus to cytoplasm") +AnnotationAssertion( "RNA-nucleus export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006405") +AnnotationAssertion(rdfs:label "RNA export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (translation) AnnotationAssertion(Annotation( "GOC:go_curators") "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.") @@ -30777,6 +31121,32 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "thyroid hormone generation") SubClassOf( ) +# Class: (protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of a protein from the cytoplasm to the nucleus.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localization to nucleus") +AnnotationAssertion( "protein import into cell nucleus") +AnnotationAssertion( "protein nucleus import") +AnnotationAssertion( "protein transport from cytoplasm to nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006606") +AnnotationAssertion(rdfs:label "protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (protein export from nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of a protein from the nucleus into the cytoplasm.") +AnnotationAssertion( "GO:0097349") +AnnotationAssertion( "protein export from cell nucleus") +AnnotationAssertion( "protein export out of nucleus") +AnnotationAssertion( "protein transport from nucleus to cytoplasm") +AnnotationAssertion( "protein-nucleus export") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:al") "copper-induced protein export from nucleus") +AnnotationAssertion( "GO:0006611") +AnnotationAssertion(rdfs:label "protein export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (vacuolar protein processing) AnnotationAssertion(Annotation( "GOC:mah") "Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.") @@ -31419,6 +31789,22 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (nucleocytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The directed movement of molecules between the nucleus and the cytoplasm.") +AnnotationAssertion( "GO:0000063") +AnnotationAssertion( "nucleocytoplasmic shuttling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006913") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.") +AnnotationAssertion(rdfs:label "nucleocytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (apoptotic process) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dhl") Annotation( "GOC:ecd") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") Annotation( "PMID:18846107") Annotation( "PMID:21494263") "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.") @@ -32575,6 +32961,29 @@ AnnotationAssertion(rdfs:label "bord EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (ovarian nurse cell to oocyte transport) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "nurse cell to oocyte transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007300") +AnnotationAssertion(rdfs:label "ovarian nurse cell to oocyte transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (cytoplasmic transport, nurse cell to oocyte) + +AnnotationAssertion(Annotation( "ISBN:0879694238") "The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007303") +AnnotationAssertion(rdfs:label "cytoplasmic transport, nurse cell to oocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (oocyte construction) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.") @@ -36710,6 +37119,17 @@ AnnotationAssertion(rdfs:label "nega EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of amino acid import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of amino acid import into a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-06T11:33:12Z") +AnnotationAssertion( "regulation of amino acid import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010958") +AnnotationAssertion(rdfs:label "regulation of amino acid import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of glucan biosynthetic process) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.") @@ -38250,6 +38670,18 @@ AnnotationAssertion( "ligand-gated monoatomic ion channel activity") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (calcium-release channel activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.") +AnnotationAssertion( "GO:0005218") +AnnotationAssertion(Annotation(rdfs:label "ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol") "Reactome:R-HSA-9717215") +AnnotationAssertion( "molecular_function") +AnnotationAssertion(Annotation( "GO:0015278") "intracellular ligand-gated calcium channel activity") +AnnotationAssertion( "GO:0015278") +AnnotationAssertion(rdfs:label "calcium-release channel activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (inorganic molecular entity transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.") @@ -38945,6 +39377,14 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (cytosolic transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances or organelles within the cytosol.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016482") +AnnotationAssertion(rdfs:label "cytosolic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein processing) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:jl") Annotation( "GOC:jsg") "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.") @@ -39632,6 +40072,14 @@ AnnotationAssertion( "secondary metabolic process") SubClassOf( ) +# Class: (cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019749") +AnnotationAssertion(rdfs:label "cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte") +EquivalentClasses( ObjectIntersectionOf( )) + # Class: (carboxylic acid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).") @@ -42309,6 +42757,21 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cytosolic ribosome) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") "A ribosome located in the cytosol.") +AnnotationAssertion( "GO:0005830") +AnnotationAssertion( "GO:0009281") +AnnotationAssertion( "GO:0030871") +AnnotationAssertion( "70S ribosome") +AnnotationAssertion( "80S ribosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0022626") +AnnotationAssertion(rdfs:label "cytosolic ribosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (passive transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.") @@ -44396,6 +44859,16 @@ AnnotationAssertion(rdfs:label "acto EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (dense core granule) + +AnnotationAssertion(Annotation( "NIF_Subcellular:sao772007592") Annotation( "PMID:14690495") "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.") +AnnotationAssertion( "NIF_Subcellular:sao772007592") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( ) "dense core vesicle") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031045") +AnnotationAssertion(rdfs:label "dense core granule") +SubClassOf( ) + # Class: (hair follicle morphogenesis) AnnotationAssertion(Annotation( "GOC:ln") "The process in which the anatomical structures of the hair follicle are generated and organized.") @@ -45677,6 +46150,15 @@ AnnotationAssertion( "bleb assembly") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (maintenance of protein location in cell cortex) + +AnnotationAssertion(Annotation( "GOC:vw") "A process in which a protein or protein complex is maintained in a specific location in the cell cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cortical protein anchoring") +AnnotationAssertion( "GO:0032065") +AnnotationAssertion(rdfs:label "maintenance of protein location in cell cortex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of nuclease activity) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") @@ -45835,6 +46317,16 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ) +# Class: (dense core granule membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a dense core granule.") +AnnotationAssertion(Annotation( "GOC:kmv") "dense core vesicle membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032127") +AnnotationAssertion(rdfs:label "dense core granule membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of synaptic transmission, cholinergic) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") @@ -46019,6 +46511,17 @@ AnnotationAssertion( "secretory granule localization") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (dense core granule localization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion(Annotation( "GOC:mah") "dense core granule localisation") +AnnotationAssertion(Annotation( "GOC:kmv") "dense core vesicle localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "dense core granule clustering") +AnnotationAssertion( "GO:0032253") +AnnotationAssertion(rdfs:label "dense core granule localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of protein polymerization) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the process of creating protein polymers.") @@ -46812,6 +47315,19 @@ AnnotationAssertion( "reproduction of a single-celled organism") SubClassOf( ) +# Class: (maintenance of protein location in cell) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization in cell") +AnnotationAssertion( "GO:0032507") +AnnotationAssertion(rdfs:label "maintenance of protein location in cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (microvillus organization) AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.") @@ -48638,6 +49154,39 @@ AnnotationAssertion( "regulation of actin filament-based process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (amino acid export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-11-14T14:27:40Z") +AnnotationAssertion( "GO:0044746") +AnnotationAssertion( "amino acid export") +AnnotationAssertion( "amino acid transmembrane export") +AnnotationAssertion( "amino acid efflux") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032973") +AnnotationAssertion(rdfs:label "amino acid export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (amino acid transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of amino acids out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "amino acid efflux from vacuole") +AnnotationAssertion( "vacuolar amino acid export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032974") +AnnotationAssertion(rdfs:label "amino acid transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (amino acid transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of amino acids into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "vacuolar amino acid import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032975") +AnnotationAssertion(rdfs:label "amino acid transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (keratinocyte activation) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:15737202") "A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.") @@ -50248,6 +50797,38 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "vacuolar amino acid transmembrane transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (basic amino acid transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034488") +AnnotationAssertion(rdfs:label "basic amino acid transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (neutral amino acid transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034489") +AnnotationAssertion(rdfs:label "neutral amino acid transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (basic amino acid transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of basic amino acids into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034490") +AnnotationAssertion(rdfs:label "basic amino acid transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (neutral amino acid transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of neutral amino acids into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034491") +AnnotationAssertion(rdfs:label "neutral amino acid transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (protein localization to chromosome) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.") @@ -51293,6 +51874,35 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (calcium-mediated signaling using intracellular calcium source) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") Annotation( "PMID:20192754") "The series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-18T11:01:08Z") +AnnotationAssertion( "calcium signaling using intracellular calcium source") +AnnotationAssertion( "calcium signalling using intracellular calcium source") +AnnotationAssertion( "calcium-mediated signalling using intracellular calcium source") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035584") +AnnotationAssertion(rdfs:label "calcium-mediated signaling using intracellular calcium source") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (calcium-mediated signaling using extracellular calcium source) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") Annotation( "PMID:20192754") "The series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-18T11:04:27Z") +AnnotationAssertion( "calcium signaling using extracellular calcium source") +AnnotationAssertion( "calcium signalling using extracellular calcium source") +AnnotationAssertion( "calcium-mediated signalling using extracellular calcium source") +AnnotationAssertion(Annotation( "GOC:BHF") "extracellular calcium influx") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035585") +AnnotationAssertion(rdfs:label "calcium-mediated signaling using extracellular calcium source") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (establishment of protein localization to extracellular region) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "The directed movement of a protein to a specific location within the extracellular region.") @@ -52531,6 +53141,18 @@ AnnotationAssertion(rdfs:label "gran EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (response to decreased oxygen levels) + +AnnotationAssertion(Annotation( "GOC:al") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-07-20T01:05:46Z") +AnnotationAssertion(Annotation( "GOC:bf") "response to lowered oxygen levels") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036293") +AnnotationAssertion(rdfs:comment "This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'.") +AnnotationAssertion(rdfs:label "response to decreased oxygen levels") +SubClassOf( ) + # Class: (lymph vessel morphogenesis) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:18093989") "The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.") @@ -53981,6 +54603,48 @@ AnnotationAssertion( "molting cycle") SubClassOf( ) +# Class: (regulation of protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.") +AnnotationAssertion( "regulation of protein import into cell nucleus") +AnnotationAssertion( "regulation of protein transport from cytoplasm to nucleus") +AnnotationAssertion( "regulation of protein-nucleus import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042306") +AnnotationAssertion(rdfs:label "regulation of protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.") +AnnotationAssertion( "positive regulation of protein import into cell nucleus") +AnnotationAssertion( "positive regulation of protein transport from cytoplasm to nucleus") +AnnotationAssertion( "positive regulation of protein-nucleus import") +AnnotationAssertion( "up regulation of protein import into nucleus") +AnnotationAssertion( "up-regulation of protein import into nucleus") +AnnotationAssertion( "upregulation of protein import into nucleus") +AnnotationAssertion( "activation of protein import into nucleus") +AnnotationAssertion( "stimulation of protein import into nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042307") +AnnotationAssertion(rdfs:label "positive regulation of protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.") +AnnotationAssertion( "down regulation of protein import into nucleus") +AnnotationAssertion( "down-regulation of protein import into nucleus") +AnnotationAssertion( "downregulation of protein import into nucleus") +AnnotationAssertion( "negative regulation of protein import into cell nucleus") +AnnotationAssertion( "negative regulation of protein transport from cytoplasm to nucleus") +AnnotationAssertion( "negative regulation of protein-nucleus import") +AnnotationAssertion( "inhibition of protein import into nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042308") +AnnotationAssertion(rdfs:label "negative regulation of protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of phosphorylation) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.") @@ -55395,6 +56059,17 @@ AnnotationAssertion( "extracellular structure organization") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (intercellular bridge organization) + +AnnotationAssertion(Annotation( "GOC:jid") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.") +AnnotationAssertion( "intercellular bridge organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "intercellular bridge organization and biogenesis") +AnnotationAssertion( "GO:0043063") +AnnotationAssertion(rdfs:label "intercellular bridge organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (positive regulation of apoptotic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.") @@ -57482,6 +58157,19 @@ AnnotationAssertion( "primary metabolic process") SubClassOf( ) +# Class: (cellular lipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.") +AnnotationAssertion( "cellular lipid breakdown") +AnnotationAssertion( "cellular lipid catabolism") +AnnotationAssertion( "cellular lipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044242") +AnnotationAssertion(rdfs:label "cellular lipid catabolic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (cellular catabolic process) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") @@ -57507,6 +58195,17 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (cellular lipid metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving lipids, as carried out by individual cells.") +AnnotationAssertion( "cellular lipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044255") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular lipid metabolic process") +SubClassOf( ) +SubClassOf( ) + # Class: (intestinal lipid catabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.emc.maricopa.edu/") "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.") @@ -57761,6 +58460,16 @@ AnnotationAssertion( "multi-multicellular organism process") SubClassOf( ) +# Class: (protein transmembrane import into intracellular organelle) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of proteins into an intracellular organelle, across a membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-11-07T15:37:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044743") +AnnotationAssertion(rdfs:label "protein transmembrane import into intracellular organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (cilium organization) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:jl") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") @@ -58114,6 +58823,24 @@ AnnotationAssertion( "cell-cell signaling involved in cell fate commitment") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (intercellular bridge) + +AnnotationAssertion(Annotation( "PMID:9635420") "A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0045171") +AnnotationAssertion(rdfs:label "intercellular bridge") +SubClassOf( ) + +# Class: (germline ring canal) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:9635420") Annotation( "PMID:9655801") "Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0045172") +AnnotationAssertion(rdfs:label "germline ring canal") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (establishment of protein localization) AnnotationAssertion(Annotation( "GOC:bf") "The directed movement of a protein to a specific location.") @@ -58126,6 +58853,19 @@ AnnotationAssertion(rdfs:label "esta EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of protein location) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.") +AnnotationAssertion( "active protein retrieval") +AnnotationAssertion( "protein retention") +AnnotationAssertion( "protein sequestering") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization") +AnnotationAssertion( "GO:0045185") +AnnotationAssertion(rdfs:label "maintenance of protein location") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (isotype switching) AnnotationAssertion(Annotation( "ISBN:0781735149") "The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.") @@ -62397,6 +63137,172 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of nucleocytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046822") +AnnotationAssertion(rdfs:label "regulation of nucleocytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleocytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.") +AnnotationAssertion( "down regulation of nucleocytoplasmic transport") +AnnotationAssertion( "down-regulation of nucleocytoplasmic transport") +AnnotationAssertion( "downregulation of nucleocytoplasmic transport") +AnnotationAssertion( "inhibition of nucleocytoplasmic transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046823") +AnnotationAssertion(rdfs:label "negative regulation of nucleocytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleocytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.") +AnnotationAssertion( "up regulation of nucleocytoplasmic transport") +AnnotationAssertion( "up-regulation of nucleocytoplasmic transport") +AnnotationAssertion( "upregulation of nucleocytoplasmic transport") +AnnotationAssertion( "activation of nucleocytoplasmic transport") +AnnotationAssertion( "stimulation of nucleocytoplasmic transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046824") +AnnotationAssertion(rdfs:label "positive regulation of nucleocytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein export from nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.") +AnnotationAssertion( "regulation of protein export from cell nucleus") +AnnotationAssertion( "regulation of protein export out of nucleus") +AnnotationAssertion( "regulation of protein transport from nucleus to cytoplasm") +AnnotationAssertion( "regulation of protein-nucleus export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046825") +AnnotationAssertion(rdfs:label "regulation of protein export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein export from nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.") +AnnotationAssertion( "down regulation of protein export from nucleus") +AnnotationAssertion( "down-regulation of protein export from nucleus") +AnnotationAssertion( "downregulation of protein export from nucleus") +AnnotationAssertion( "negative regulation of protein export from cell nucleus") +AnnotationAssertion( "negative regulation of protein export out of nucleus") +AnnotationAssertion( "negative regulation of protein transport from nucleus to cytoplasm") +AnnotationAssertion( "negative regulation of protein-nucleus export") +AnnotationAssertion( "inhibition of protein export from nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046826") +AnnotationAssertion(rdfs:label "negative regulation of protein export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of protein export from nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.") +AnnotationAssertion( "positive regulation of protein export from cell nucleus") +AnnotationAssertion( "positive regulation of protein export out of nucleus") +AnnotationAssertion( "positive regulation of protein transport from nucleus to cytoplasm") +AnnotationAssertion( "positive regulation of protein-nucleus export") +AnnotationAssertion( "up regulation of protein export from nucleus") +AnnotationAssertion( "up-regulation of protein export from nucleus") +AnnotationAssertion( "upregulation of protein export from nucleus") +AnnotationAssertion( "activation of protein export from nucleus") +AnnotationAssertion( "stimulation of protein export from nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046827") +AnnotationAssertion(rdfs:label "positive regulation of protein export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of RNA import into nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.") +AnnotationAssertion( "regulation of RNA import into cell nucleus") +AnnotationAssertion( "regulation of RNA transport from cytoplasm to nucleus") +AnnotationAssertion( "regulation of RNA-nucleus import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046828") +AnnotationAssertion(rdfs:label "regulation of RNA import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of RNA import into nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.") +AnnotationAssertion( "down regulation of RNA import into nucleus") +AnnotationAssertion( "down-regulation of RNA import into nucleus") +AnnotationAssertion( "downregulation of RNA import into nucleus") +AnnotationAssertion( "negative regulation of RNA import into cell nucleus") +AnnotationAssertion( "negative regulation of RNA transport from cytoplasm to nucleus") +AnnotationAssertion( "negative regulation of RNA-nucleus import") +AnnotationAssertion( "inhibition of RNA import into nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046829") +AnnotationAssertion(rdfs:label "negative regulation of RNA import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of RNA import into nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.") +AnnotationAssertion( "positive regulation of RNA import into cell nucleus") +AnnotationAssertion( "positive regulation of RNA transport from cytoplasm to nucleus") +AnnotationAssertion( "positive regulation of RNA-nucleus import") +AnnotationAssertion( "up regulation of RNA import into nucleus") +AnnotationAssertion( "up-regulation of RNA import into nucleus") +AnnotationAssertion( "upregulation of RNA import into nucleus") +AnnotationAssertion( "activation of RNA import into nucleus") +AnnotationAssertion( "stimulation of RNA import into nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046830") +AnnotationAssertion(rdfs:label "positive regulation of RNA import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of RNA export from nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.") +AnnotationAssertion( "regulation of RNA export from cell nucleus") +AnnotationAssertion( "regulation of RNA export out of nucleus") +AnnotationAssertion( "regulation of RNA transport from nucleus to cytoplasm") +AnnotationAssertion( "regulation of RNA-nucleus export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046831") +AnnotationAssertion(rdfs:label "regulation of RNA export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of RNA export from nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.") +AnnotationAssertion( "down regulation of RNA export from nucleus") +AnnotationAssertion( "down-regulation of RNA export from nucleus") +AnnotationAssertion( "downregulation of RNA export from nucleus") +AnnotationAssertion( "negative regulation of RNA export from cell nucleus") +AnnotationAssertion( "negative regulation of RNA export out of nucleus") +AnnotationAssertion( "negative regulation of RNA transport from nucleus to cytoplasm") +AnnotationAssertion( "negative regulation of RNA-nucleus export") +AnnotationAssertion( "inhibition of RNA export from nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046832") +AnnotationAssertion(rdfs:label "negative regulation of RNA export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of RNA export from nucleus) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.") +AnnotationAssertion( "positive regulation of RNA export from cell nucleus") +AnnotationAssertion( "positive regulation of RNA export out of nucleus") +AnnotationAssertion( "positive regulation of RNA transport from nucleus to cytoplasm") +AnnotationAssertion( "positive regulation of RNA-nucleus export") +AnnotationAssertion( "up regulation of RNA export from nucleus") +AnnotationAssertion( "up-regulation of RNA export from nucleus") +AnnotationAssertion( "upregulation of RNA export from nucleus") +AnnotationAssertion( "activation of RNA export from nucleus") +AnnotationAssertion( "stimulation of RNA export from nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046833") +AnnotationAssertion(rdfs:label "positive regulation of RNA export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (hydroxyapatite binding) AnnotationAssertion(Annotation( "PMID:2438276") "Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.") @@ -67994,6 +68900,17 @@ AnnotationAssertion( "positive regulation of striated muscle cell differentiation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (nuclear export) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances out of the nucleus.") +AnnotationAssertion( "export from nucleus") +AnnotationAssertion( "nucleus export") +AnnotationAssertion( "substance nuclear export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051168") +AnnotationAssertion(rdfs:label "nuclear export") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (nuclear transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of, or within the nucleus.") @@ -68005,6 +68922,19 @@ AnnotationAssertion( "nuclear transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (import into nucleus) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into the nucleus.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-19T15:26:34Z") +AnnotationAssertion( "GO:1902593") +AnnotationAssertion( "nuclear import") +AnnotationAssertion( "nuclear translocation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051170") +AnnotationAssertion(rdfs:label "import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (regulation of nitrogen compound metabolic process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") @@ -68069,6 +68999,45 @@ AnnotationAssertion( "localization") SubClassOf( ) +# Class: (sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "The process of binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "calcium ion (Ca2+) retention") +AnnotationAssertion( "calcium ion (Ca2+) sequestering") +AnnotationAssertion( "calcium ion (Ca2+) sequestration") +AnnotationAssertion( "calcium ion (Ca2+) storage") +AnnotationAssertion( "retention of calcium ion (Ca2+)") +AnnotationAssertion( "sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "storage of calcium ion (Ca2+)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "calcium ion storage activity") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) transport") +AnnotationAssertion( "GO:0051208") +AnnotationAssertion(rdfs:label "sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") Annotation( "GOC:mtg_lung") Annotation( "PMID:1814929") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.") +AnnotationAssertion( "calcium ion (Ca2+) mobilization") +AnnotationAssertion( "calcium mobilization") +AnnotationAssertion( "cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "release of sequestered calcium ion into cytoplasm") +AnnotationAssertion( "release of stored calcium ion (Ca2+)") +AnnotationAssertion( "release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "cytosolic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "cytosolic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051209") +AnnotationAssertion(rdfs:label "release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cartilage development) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:23251424") "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -68141,6 +69110,18 @@ AnnotationAssertion( "establishment of localization") SubClassOf( ) +# Class: (maintenance of location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.") +AnnotationAssertion( "maintenance of localization") +AnnotationAssertion( "retention") +AnnotationAssertion( "sequestering") +AnnotationAssertion( "storage") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051235") +AnnotationAssertion(rdfs:label "maintenance of location") +SubClassOf( ) + # Class: (establishment of RNA localization) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of RNA to a specific location.") @@ -68371,6 +69352,129 @@ AnnotationAssertion( "chromosome organization") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") +AnnotationAssertion( "regulation of release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+)") +AnnotationAssertion( "regulation of calcium ion (Ca2+) mobilization") +AnnotationAssertion( "regulation of calcium mobilization") +AnnotationAssertion( "regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "regulation of cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051279") +AnnotationAssertion(rdfs:label "regulation of release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) mobilization") +AnnotationAssertion( "negative regulation of calcium mobilization") +AnnotationAssertion( "negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of sequestered calcium ion into cytoplasm") +AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "down regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "down-regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "downregulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "negative regulation of cytosolic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of cytosolic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "inhibition of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051280") +AnnotationAssertion(rdfs:label "negative regulation of release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) mobilization") +AnnotationAssertion( "positive regulation of calcium mobilization") +AnnotationAssertion( "positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of sequestered calcium ion into cytoplasm") +AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "positive regulation of cytosolic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of cytosolic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "up regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "up-regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "upregulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "activation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "stimulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051281") +AnnotationAssertion(rdfs:label "positive regulation of release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "regulation of calcium ion (Ca2+) retention") +AnnotationAssertion( "regulation of calcium ion (Ca2+) sequestering") +AnnotationAssertion( "regulation of calcium ion (Ca2+) sequestration") +AnnotationAssertion( "regulation of calcium ion (Ca2+) storage") +AnnotationAssertion( "regulation of retention of calcium ion (Ca2+)") +AnnotationAssertion( "regulation of sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "regulation of sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "regulation of storage of calcium ion (Ca2+)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051282") +AnnotationAssertion(rdfs:label "regulation of sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "down regulation of sequestering of calcium ion") +AnnotationAssertion( "down-regulation of sequestering of calcium ion") +AnnotationAssertion( "downregulation of sequestering of calcium ion") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) retention") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) sequestering") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) sequestration") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) storage") +AnnotationAssertion( "negative regulation of retention of calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of storage of calcium ion (Ca2+)") +AnnotationAssertion( "inhibition of sequestering of calcium ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051283") +AnnotationAssertion(rdfs:label "negative regulation of sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) retention") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) sequestering") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) sequestration") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) storage") +AnnotationAssertion( "positive regulation of retention of calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of storage of calcium ion (Ca2+)") +AnnotationAssertion( "up regulation of sequestering of calcium ion") +AnnotationAssertion( "up-regulation of sequestering of calcium ion") +AnnotationAssertion( "upregulation of sequestering of calcium ion") +AnnotationAssertion( "activation of sequestering of calcium ion") +AnnotationAssertion( "stimulation of sequestering of calcium ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051284") +AnnotationAssertion(rdfs:label "positive regulation of sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (cell division) AnnotationAssertion(Annotation( "GOC:di") Annotation( "GOC:go_curators") Annotation( "GOC:pr") "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.") @@ -68686,6 +69790,30 @@ AnnotationAssertion(rdfs:label "myob EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of protein location in nucleus) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.") +AnnotationAssertion( "maintenance of nuclear protein localization") +AnnotationAssertion( "maintenance of protein location in cell nucleus") +AnnotationAssertion( "nuclear protein retention") +AnnotationAssertion( "nuclear protein sequestering") +AnnotationAssertion( "nuclear protein sequestration") +AnnotationAssertion( "protein retention in nucleus") +AnnotationAssertion( "protein sequestration in nucleus") +AnnotationAssertion( "protein storage in nucleus") +AnnotationAssertion( "protein-nuclear retention") +AnnotationAssertion( "sequestration of protein in nucleus") +AnnotationAssertion( "storage of protein in nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization in nucleus") +AnnotationAssertion( "GO:0051457") +AnnotationAssertion(rdfs:label "maintenance of protein location in nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (corticotropin secretion) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:11027914") "The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.") @@ -68853,6 +69981,43 @@ AnnotationAssertion( "positive regulation of keratinocyte migration") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of neurotransmitter uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of neurotransmitter import") +AnnotationAssertion( "regulation of neurotransmitter reuptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051580") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of neurotransmitter uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neurotransmitter uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") +AnnotationAssertion( "down regulation of neurotransmitter uptake") +AnnotationAssertion( "down-regulation of neurotransmitter uptake") +AnnotationAssertion( "downregulation of neurotransmitter uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neurotransmitter import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051581") +AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neurotransmitter uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of neurotransmitter import") +AnnotationAssertion( "up regulation of neurotransmitter uptake") +AnnotationAssertion( "up-regulation of neurotransmitter uptake") +AnnotationAssertion( "upregulation of neurotransmitter uptake") +AnnotationAssertion( "activation of neurotransmitter uptake") +AnnotationAssertion( "stimulation of neurotransmitter uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051582") +AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of neurotransmitter transport) AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -68957,6 +70122,51 @@ AnnotationAssertion( "histamine transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "histamine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051615") +AnnotationAssertion(rdfs:label "histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of histamine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051616") +AnnotationAssertion(rdfs:label "regulation of histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.") +AnnotationAssertion( "down regulation of histamine uptake") +AnnotationAssertion( "down-regulation of histamine uptake") +AnnotationAssertion( "downregulation of histamine uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of histamine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051617") +AnnotationAssertion(rdfs:label "negative regulation of histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of histamine import") +AnnotationAssertion( "up regulation of histamine uptake") +AnnotationAssertion( "up-regulation of histamine uptake") +AnnotationAssertion( "upregulation of histamine uptake") +AnnotationAssertion( "activation of histamine uptake") +AnnotationAssertion( "stimulation of histamine uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051618") +AnnotationAssertion(rdfs:label "positive regulation of histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (norepinephrine uptake) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") @@ -69205,6 +70415,50 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ) +# Class: (maintenance of location in cell) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.") +AnnotationAssertion( "cellular retention") +AnnotationAssertion( "cellular sequestering") +AnnotationAssertion( "cellular storage") +AnnotationAssertion( "intracellular retention") +AnnotationAssertion( "intracellular sequestering") +AnnotationAssertion( "intracellular storage") +AnnotationAssertion( "maintenance of intracellular localization") +AnnotationAssertion( "maintenance of localization within cell") +AnnotationAssertion( "retention within cell") +AnnotationAssertion( "sequestering within cell") +AnnotationAssertion( "storage within cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of cellular localization") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of localization in cell") +AnnotationAssertion( "GO:0051651") +AnnotationAssertion(rdfs:label "maintenance of location in cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (maintenance of chromosome location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of chromosome localization") +AnnotationAssertion( "GO:0051652") +AnnotationAssertion(rdfs:label "maintenance of chromosome location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of vesicle location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of vesicle localization") +AnnotationAssertion( "GO:0051655") +AnnotationAssertion(rdfs:label "maintenance of vesicle location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (establishment of organelle localization) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of an organelle to a specific location.") @@ -69215,6 +70469,27 @@ AnnotationAssertion(rdfs:label "esta EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of organelle location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of organelle localization") +AnnotationAssertion( "GO:0051657") +AnnotationAssertion(rdfs:label "maintenance of organelle location") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (maintenance of nucleus location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "maintenance of cell nucleus location") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of nucleus localization") +AnnotationAssertion( "GO:0051658") +AnnotationAssertion(rdfs:label "maintenance of nucleus location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (localization within membrane) AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.") @@ -69255,6 +70530,18 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ) +# Class: (maintenance of Golgi location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "maintenance of Golgi apparatus localization") +AnnotationAssertion( "maintenance of Golgi body localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of Golgi localization") +AnnotationAssertion( "GO:0051684") +AnnotationAssertion(rdfs:label "maintenance of Golgi location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (response to other organism) AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.") @@ -75221,6 +76508,18 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (dense core granule organization) + +AnnotationAssertion(Annotation( "GOC:dph") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-01T09:34:37Z") +AnnotationAssertion(Annotation( "GOC:mah") "dense core granule organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061109") +AnnotationAssertion(rdfs:label "dense core granule organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (pancreas morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.") @@ -76789,6 +78088,17 @@ AnnotationAssertion(rdfs:label "inte EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (release of sequestered calcium ion into cytosol by Golgi) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-07-27T02:29:43Z") +AnnotationAssertion( "Golgi calcium ion export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061454") +AnnotationAssertion(rdfs:label "release of sequestered calcium ion into cytosol by Golgi") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (reproductive system development) AnnotationAssertion(Annotation( "GOC:dph") "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.") @@ -77430,6 +78740,17 @@ AnnotationAssertion(rdfs:label "tran EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (cytosolic lipolysis) + +AnnotationAssertion(Annotation( "GOC:autophagy") "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-07-08T13:42:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061725") +AnnotationAssertion(rdfs:label "cytosolic lipolysis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (secretory granule maturation) AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "PMID:16618809") "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.") @@ -78746,6 +80067,24 @@ AnnotationAssertion( "thyroid-stimulating hormone secretion") SubClassOf( ) +# Class: (response to oxygen levels) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070482") +AnnotationAssertion(rdfs:label "response to oxygen levels") +SubClassOf( ) + +# Class: (detection of hypoxia) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.") +AnnotationAssertion(Annotation( "GOC:vk") "detection of reduced oxygen levels") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070483") +AnnotationAssertion(rdfs:label "detection of hypoxia") +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of microtubule cytoskeleton organization) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.") @@ -79279,6 +80618,18 @@ AnnotationAssertion( "cellular response to ammonium ion") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (cellular response to calcium ion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T03:55:01Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to Ca2+ ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071277") +AnnotationAssertion(rdfs:label "cellular response to calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cellular response to iron ion) AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.") @@ -83133,6 +84484,20 @@ AnnotationAssertion(rdfs:label "esta EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of protein localization in organelle) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:09:13Z") +AnnotationAssertion(Annotation( "GOC:mah") "maintenance of protein localisation to organelle") +AnnotationAssertion( "maintenance of protein localization to organelle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072595") +AnnotationAssertion(rdfs:label "maintenance of protein localization in organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (protein localization to membrane) AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a specific location in a membrane.") @@ -83188,6 +84553,18 @@ AnnotationAssertion(rdfs:label "esta EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of protein location in vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:56:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072667") +AnnotationAssertion(rdfs:label "maintenance of protein location in vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (multinuclear osteoclast differentiation) AnnotationAssertion(Annotation( "CL:0000779") Annotation( "GOC:mah") Annotation( "PMID:12713016") "The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") @@ -83724,6 +85101,22 @@ AnnotationAssertion( "G protein-coupled receptor signaling pathway involved in heart process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (L-glutamate transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0089704") +AnnotationAssertion(rdfs:label "L-glutamate transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (L-histidine transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0089708") +AnnotationAssertion(rdfs:label "L-histidine transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (L-histidine transmembrane transport) AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-histidine across a membrane.") @@ -83732,6 +85125,23 @@ AnnotationAssertion( "L-histidine transmembrane transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (amino acid import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:8195186") "The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-11-14T14:21:41Z") +AnnotationAssertion( "GO:0043092") +AnnotationAssertion( "GO:0044745") +AnnotationAssertion( "GO:1902837") +AnnotationAssertion( "L-amino acid import") +AnnotationAssertion( "amino acid transmembrane import") +AnnotationAssertion( "amino acid import into cell") +AnnotationAssertion( "L-amino acid uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0089718") +AnnotationAssertion(rdfs:label "amino acid import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (primitive streak formation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.") @@ -84048,6 +85458,16 @@ AnnotationAssertion(rdfs:label "esta EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (Golgi to lysosome transport) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of substances from the Golgi to lysosomes.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T08:35:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090160") +AnnotationAssertion(rdfs:label "Golgi to lysosome transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (establishment of epithelial cell polarity) AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization of an epithelial cell.") @@ -84537,6 +85957,17 @@ AnnotationAssertion(rdfs:label "prot EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (glutamate transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:tb") "The directed movement of glutamate into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-09-24T14:12:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "vacuolar glutamate import") +AnnotationAssertion( "GO:0090454") +AnnotationAssertion(rdfs:label "glutamate transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (intracellular glutamate homeostasis) AnnotationAssertion(Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell.") @@ -84593,6 +86024,29 @@ AnnotationAssertion(rdfs:label "mese EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (L-histidine transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:al") "The directed movement of L-histidine into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-12-14T11:25:52Z") +AnnotationAssertion( "GO:0090457") +AnnotationAssertion( "histidine transmembrane import into vacuole") +AnnotationAssertion(Annotation( "GOC:tb") "vacuolar histidine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090513") +AnnotationAssertion(rdfs:label "L-histidine transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:al") "The directed movement of L-glutamate into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-12-14T11:25:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090515") +AnnotationAssertion(rdfs:label "L-glutamate transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (podocyte cell migration) AnnotationAssertion(Annotation( "GOC:pm") Annotation( "PMID:21402783") "The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.") @@ -85441,6 +86895,20 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (calcium ion transmembrane import into cytosol) + +AnnotationAssertion(Annotation( "GOC:vw") "A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23015"^^xsd:anyURI) +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-01-23T11:05:13Z") +AnnotationAssertion( "GO:0060401") +AnnotationAssertion( "calcium transmembrane import into cytosol") +AnnotationAssertion( "cytosolic calcium ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097553") +AnnotationAssertion(rdfs:label "calcium ion transmembrane import into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (vacuole fusion) AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "Wikipedia:Vacuole") "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.") @@ -85688,6 +87156,27 @@ AnnotationAssertion( "defense response to other organism") SubClassOf( ) +# Class: (maintenance of protein complex location) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-11-15T18:20:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098544") +AnnotationAssertion(rdfs:label "maintenance of protein complex location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of protein complex location in cytoplasm) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-11-15T20:49:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098545") +AnnotationAssertion(rdfs:label "maintenance of protein complex location in cytoplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (bounding membrane of organelle) AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer that forms the outer-most layer of an organelle.") @@ -85929,6 +87418,78 @@ AnnotationAssertion( "regulation of synaptic vesicle cycle") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (calcium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-02-07T13:07:59Z") +AnnotationAssertion( "GO:1990035") +AnnotationAssertion( "calcium ion import into cell") +AnnotationAssertion(Annotation( "GOC:vw") "calcium ion uptake into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098703") +AnnotationAssertion(rdfs:label "calcium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (carbohydrate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-05-31T02:45:02Z") +AnnotationAssertion( "GO:0097319") +AnnotationAssertion( "carbohydrate import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098704") +AnnotationAssertion(rdfs:label "carbohydrate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (glucose import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-12-06T14:54:07Z") +AnnotationAssertion( "GO:0061490") +AnnotationAssertion( "GO:1990821") +AnnotationAssertion( "glucose import into cell") +AnnotationAssertion( "high affinity glucose import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098708") +AnnotationAssertion(rdfs:label "glucose import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (iron ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:8321236") "The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-20T08:29:00Z") +AnnotationAssertion( "GO:0097459") +AnnotationAssertion( "GO:0097460") +AnnotationAssertion( "GO:0098707") +AnnotationAssertion( "iron ion import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "ferrous ion import into cell") +AnnotationAssertion( "ferrous iron import across plasma membrane") +AnnotationAssertion( "ferrous iron import into cell") +AnnotationAssertion(Annotation( "GOC:mah") "iron import into cell") +AnnotationAssertion( "GO:0098711") +AnnotationAssertion(rdfs:label "iron ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-06-12T12:32:47Z") +AnnotationAssertion( "GO:1903802") +AnnotationAssertion( "GO:1990123") +AnnotationAssertion( "L-glutamate(1-) import across plasma membrane") +AnnotationAssertion( "L-glutamate import into cell") +AnnotationAssertion( "L-glutamate(1-) import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098712") +AnnotationAssertion(rdfs:label "L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (asymmetric stem cell division) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:18513950") "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.") @@ -85971,6 +87532,15 @@ AnnotationAssertion(rdfs:label "skel EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098739") +AnnotationAssertion(rdfs:label "import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (cerebellar neuron development) AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") @@ -86564,6 +88134,16 @@ AnnotationAssertion(rdfs:label "G pr EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (neuronal dense core vesicle) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "ISBN:978-0-07-181001-2") Annotation( "Wikipedia:Neuropeptide&oldid=713905176") "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098992") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neuronal dense core vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (vesicle-mediated transport in synapse) AnnotationAssertion(Annotation( "GOC:dos") "Any vesicle-mediated transport that occurs in a synapse.") @@ -86575,6 +88155,24 @@ EquivalentClasses( ObjectIntersection SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (neuronal dense core vesicle membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding a neuronal dense core vesicle.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099012") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neuronal dense core vesicle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuronal dense core vesicle organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099014") +AnnotationAssertion(rdfs:label "neuronal dense core vesicle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (presynapse assembly) AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:24449494") "The aggregation, arrangement and bonding together of a set of components to form a presynapse.") @@ -87004,6 +88602,46 @@ AnnotationAssertion( "vesicle cytoskeletal trafficking") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (dense core granule cytoskeletal transport) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.") +AnnotationAssertion( "dense core vesicle cytoskeletal trafficking") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099519") +AnnotationAssertion(rdfs:label "dense core granule cytoskeletal transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytosolic region) + +AnnotationAssertion(Annotation( "GOC:dos") "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.") +AnnotationAssertion( "region of cytosol") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099522") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytosolic region") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynaptic cytosol) + +AnnotationAssertion(Annotation( "GOC:dos") "The region of the cytosol consisting of all cytosol that is part of the presynapse.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099523") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (postsynaptic cytosol) + +AnnotationAssertion(Annotation( "GOC:dos") "The region of the cytosol consisting of all cytosol that is part of the postsynapse.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099524") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (G protein-coupled neurotransmitter receptor activity) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:fj") Annotation( "GOC:mah") "Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") @@ -87299,6 +88937,26 @@ AnnotationAssertion(rdfs:label "G pr EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (release of sequestered calcium ion into presynaptic cytosol) + +AnnotationAssertion(Annotation( "GOC:dos") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099585") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "release of sequestered calcium ion into presynaptic cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (release of sequestered calcium ion into postsynaptic cytosol) + +AnnotationAssertion(Annotation( "GOC:dos") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099586") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "release of sequestered calcium ion into postsynaptic cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (serotonin receptor activity) AnnotationAssertion(Annotation( "GOC:dos") "Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.") @@ -88543,6 +90201,17 @@ AnnotationAssertion( "extracellular vesicle biogenesis") SubClassOf( ) +# Class: (export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:pg") "The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "pg") +AnnotationAssertion( "2017-10-24T14:38:16Z") +AnnotationAssertion( "efflux") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0140115") +AnnotationAssertion(rdfs:label "export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (positive regulation of lymphocyte chemotaxis) AnnotationAssertion(Annotation( "PMID:19255442") "Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.") @@ -88553,6 +90222,26 @@ AnnotationAssertion( "positive regulation of lymphocyte chemotaxis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (calcium ion import into vacuole) + +AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:8628289") "The directed movement of calcium cations into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "pg") +AnnotationAssertion( "2017-12-13T15:15:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0140146") +AnnotationAssertion(rdfs:label "calcium ion import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (ammonium import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:16999738") "The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pg") +AnnotationAssertion( "2018-01-26T12:39:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0140157") +AnnotationAssertion(rdfs:label "ammonium import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (serotonin-gated cation-selective signaling pathway) AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "PMID:25392484") Annotation( "PMID:27764665") "The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.") @@ -88797,6 +90486,16 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (hexose import across plasma membrane) + +AnnotationAssertion(Annotation( "PMID:10735857") "The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pg") +AnnotationAssertion( "2018-10-01T08:49:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0140271") +AnnotationAssertion(rdfs:label "hexose import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (DNA-binding transcription factor binding) AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.") @@ -88996,6 +90695,17 @@ AnnotationAssertion( "ammonium excretion") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (cytosol to Golgi apparatus transport) + +AnnotationAssertion(Annotation( "PMID:28373556") "The directed movement of substances from the cytosol into the Golgi apparatus of a cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21524"^^xsd:anyURI) +AnnotationAssertion( "pg") +AnnotationAssertion( "2022-05-16T06:59:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0140820") +AnnotationAssertion(rdfs:label "cytosol to Golgi apparatus transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (multicellular organismal-level chemical homeostasis) AnnotationAssertion(Annotation( "GOC:curators") "A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.") @@ -90539,6 +92249,45 @@ AnnotationAssertion( "positive regulation of apoptotic process involved in metanephric nephron tubule development") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of cytoplasmic translational elongation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2012-04-03T05:07:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1900247") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytoplasmic translational elongation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2012-04-03T05:07:14Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic translational elongation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic translational elongation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic translational elongation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic translational elongation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1900248") +AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of cytoplasmic translational elongation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2012-04-03T05:07:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic translational elongation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic translational elongation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic translational elongation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic translational elongation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1900249") +AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (negative regulation of defense response to insect) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22474183") "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.") @@ -90740,6 +92489,47 @@ AnnotationAssertion( "positive regulation of glutamate receptor signaling pathway") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of glycine import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of glycine import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:40:11Z") +AnnotationAssertion( "regulation of glycine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1900923") +AnnotationAssertion(rdfs:label "regulation of glycine import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glycine import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:40:32Z") +AnnotationAssertion( "negative regulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glycine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1900924") +AnnotationAssertion(rdfs:label "negative regulation of glycine import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glycine import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of glycine import.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:40:40Z") +AnnotationAssertion( "positive regulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glycine import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glycine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1900925") +AnnotationAssertion(rdfs:label "positive regulation of glycine import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of calcium ion transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.") @@ -91041,6 +92831,29 @@ AnnotationAssertion( "positive regulation of formation of translation initiation ternary complex") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (positive regulation of calcium-mediated signaling involved in cellular response to calcium ion) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-07-27T10:57:56Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium-mediated signalling involved in cellular response to calcium ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium-mediated signaling involved in cellular response to calcium ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium-mediated signaling involved in response to calcium ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium-mediated signaling involved in cellular response to calcium ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium-mediated signaling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium-mediated signaling involved in cellular response to calcium ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "stimulation of calcium-mediated signaling involved in cellular response to calcium ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901197") +AnnotationAssertion(rdfs:label "positive regulation of calcium-mediated signaling involved in cellular response to calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of extracellular matrix assembly) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of extracellular matrix assembly.") @@ -91489,6 +93302,16 @@ AnnotationAssertion( "positive regulation of chorionic trophoblast cell proliferation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of Golgi calcium ion export) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of Golgi calcium ion export.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-10-03T07:26:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901472") +AnnotationAssertion(rdfs:label "regulation of Golgi calcium ion export") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of lymphangiogenesis) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:20133819") "Any process that modulates the frequency, rate or extent of lymphangiogenesis.") @@ -92695,6 +94518,95 @@ AnnotationAssertion(rdfs:label "posi EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +# Class: (dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement a dense core granule within a cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:00:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "dense core vesicle transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901950") +AnnotationAssertion(rdfs:comment "goslim_synapse") +AnnotationAssertion(rdfs:label "dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of anterograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901951") +AnnotationAssertion(rdfs:label "regulation of anterograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of anterograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:30Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of anterograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901952") +AnnotationAssertion(rdfs:label "negative regulation of anterograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of anterograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of anterograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901953") +AnnotationAssertion(rdfs:label "positive regulation of anterograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of retrograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901954") +AnnotationAssertion(rdfs:label "regulation of retrograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of retrograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retrograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901955") +AnnotationAssertion(rdfs:label "negative regulation of retrograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of retrograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retrograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901956") +AnnotationAssertion(rdfs:label "positive regulation of retrograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of cell proliferation involved in outflow tract morphogenesis) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:21419760") "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.") @@ -97464,6 +99376,55 @@ AnnotationAssertion( "positive regulation of DNA catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of cytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25049409") "Any process that modulates the frequency, rate or extent of cytoplasmic transport.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-11-24T13:38:17Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cytoplasmic streaming") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903649") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25049409") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-11-24T13:38:26Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cytoplasmic streaming") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903650") +AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25049409") "Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-11-24T13:38:34Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic streaming") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic streaming") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903651") +AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (acinar cell of sebaceous gland differentiation) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "PMID:17018284") Annotation( "PMID:18334552") Annotation( "PMID:19944183") "The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.") @@ -97797,6 +99758,34 @@ AnnotationAssertion( "regulation of amino acid transmembrane transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (glycine import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000075") Annotation( "PMID:23895341") "The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-05-11T01:16:45Z") +AnnotationAssertion( "GO:0036233") +AnnotationAssertion( "glycine import") +AnnotationAssertion( "glycine import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903804") +AnnotationAssertion(rdfs:label "glycine import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (L-histidine import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000075") Annotation( "PMID:23895341") "The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-10-05T10:20:50Z") +AnnotationAssertion( "GO:0061460") +AnnotationAssertion( "GO:0090466") +AnnotationAssertion( "L-histidine import") +AnnotationAssertion( "histidine import") +AnnotationAssertion( "L-histidine import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903810") +AnnotationAssertion(rdfs:label "L-histidine import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (organic acid transmembrane transport) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000069") "The process in which an organic acid is transported across a membrane.") @@ -98303,6 +100292,22 @@ AnnotationAssertion(rdfs:label "posi EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +# Class: (iron ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GOC:rl") Annotation( "GO_REF:0000074") Annotation( "PMID:15514116") "The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-09-03T13:01:37Z") +AnnotationAssertion( "GO:1903414") +AnnotationAssertion( "ferrous iron export") +AnnotationAssertion( "ferrous iron export across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "iron cation export") +AnnotationAssertion( "iron(2+) export") +AnnotationAssertion( "GO:1903988") +AnnotationAssertion(rdfs:comment "An example of this is mouse ferroportin (symbol Slc40a1, UniProtKB identifier: Q9JHI9).") +AnnotationAssertion(rdfs:label "iron ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (regulation of sebum secreting cell proliferation) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "GO_REF:0000058") Annotation( "PMID:16901790") "Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.") @@ -98544,6 +100549,58 @@ AnnotationAssertion( "positive regulation of epithelial cell apoptotic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of iron export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:15514116") "Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "kom") +AnnotationAssertion( "2015-03-16T15:36:37Z") +AnnotationAssertion( "regulation of ferrous iron export") +AnnotationAssertion( "regulation of iron(2+) export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904038") +AnnotationAssertion(rdfs:label "regulation of iron export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of iron export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:15514116") "Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "kom") +AnnotationAssertion( "2015-03-16T15:36:43Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ferrous iron export") +AnnotationAssertion( "negative regulation of iron(2+) export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904039") +AnnotationAssertion(rdfs:label "negative regulation of iron export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of iron export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:15514116") "Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "kom") +AnnotationAssertion( "2015-03-16T15:36:49Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ferrous iron export") +AnnotationAssertion( "positive regulation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of iron(2+) export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ferrous iron export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of iron(2+) export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904040") +AnnotationAssertion(rdfs:label "positive regulation of iron export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (response to aldosterone) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:17644563") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.") @@ -100171,6 +102228,65 @@ AnnotationAssertion( "positive regulation of calcium ion transmembrane transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of iron ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:18353247") "Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2015-03-04T14:37:36Z") +AnnotationAssertion( "GO:1903989") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ferrous ion import into cell") +AnnotationAssertion( "regulation of ferrous iron import across plasma membrane") +AnnotationAssertion( "regulation of ferrous iron import into cell") +AnnotationAssertion( "GO:1904438") +AnnotationAssertion(rdfs:label "regulation of iron ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of iron ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:18353247") "Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2015-07-06T13:49:58Z") +AnnotationAssertion( "GO:1903990") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ferrous iron import across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ferrous iron import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ferrous iron import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ferrous iron import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ferrous ion import into cell") +AnnotationAssertion( "negative regulation of ferrous iron import across plasma membrane") +AnnotationAssertion( "negative regulation of ferrous iron import into cell") +AnnotationAssertion( "GO:1904439") +AnnotationAssertion(rdfs:label "negative regulation of iron ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of iron ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:18353247") "Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2015-07-06T13:50:04Z") +AnnotationAssertion( "GO:1903991") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ferrous iron import across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ferrous ion import into cell") +AnnotationAssertion( "positive regulation of ferrous iron import across plasma membrane") +AnnotationAssertion( "positive regulation of ferrous iron import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ferrous iron import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ferrous iron import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ferrous ion import into cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ferrous iron import across plasma membrane") +AnnotationAssertion( "GO:1904440") +AnnotationAssertion(rdfs:label "positive regulation of iron ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (negative regulation of neuronal action potential) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25126967") "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.") @@ -100863,6 +102979,46 @@ AnnotationAssertion( "peptide transmembrane transporter activity") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (regulation of cytoplasmic translational initiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:12242291") "Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21560"^^xsd:anyURI) +AnnotationAssertion( "dos") +AnnotationAssertion( "2015-09-25T14:39:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904688") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cytoplasmic translational initiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:12242291") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2015-09-25T14:39:44Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic translational initiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic translational initiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic translational initiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic translational initiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904689") +AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytoplasmic translational initiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:12242291") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2015-09-25T14:39:50Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic translational initiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic translational initiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic translational initiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic translational initiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904690") +AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (negative regulation of type B pancreatic cell proliferation) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24055447") "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.") @@ -101772,6 +103928,58 @@ AnnotationAssertion( "positive regulation of euchromatin binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22699897") "Any process that modulates the frequency, rate or extent of dense core granule transport.") +AnnotationAssertion( "es") +AnnotationAssertion( "2015-11-11T10:40:10Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dense core vesicle transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904809") +AnnotationAssertion(rdfs:comment "cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).") +AnnotationAssertion(rdfs:label "regulation of dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22699897") "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.") +AnnotationAssertion( "es") +AnnotationAssertion( "2015-11-11T10:40:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dense core vesicle transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904810") +AnnotationAssertion(rdfs:comment "cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).") +AnnotationAssertion(rdfs:label "negative regulation of dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22699897") "Any process that activates or increases the frequency, rate or extent of dense core granule transport.") +AnnotationAssertion( "es") +AnnotationAssertion( "2015-11-11T10:40:25Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dense core vesicle transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dense core vesicle transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1904811") +AnnotationAssertion(rdfs:comment "cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).") +AnnotationAssertion(rdfs:label "positive regulation of dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (serous membrane development) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000094") Annotation( "PMID:15840053") "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.") @@ -105212,6 +107420,32 @@ AnnotationAssertion( "positive regulation of artery morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of calcium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17640527") "Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2016-11-11T09:26:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1905664") +AnnotationAssertion(rdfs:comment "An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).") +AnnotationAssertion(rdfs:label "regulation of calcium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of calcium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17640527") "Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2016-11-11T09:26:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion import across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1905665") +AnnotationAssertion(rdfs:comment "An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).") +AnnotationAssertion(rdfs:label "positive regulation of calcium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of lysosome organization) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25561470") "Any process that modulates the frequency, rate or extent of lysosome organization.") @@ -105876,6 +108110,58 @@ AnnotationAssertion( "pharyngeal gland morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of calcium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.") +AnnotationAssertion( "rph") +AnnotationAssertion( "2017-02-07T13:20:39Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of calcium ion efflux from cell") +AnnotationAssertion( "regulation of calcium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1905912") +AnnotationAssertion(rdfs:label "regulation of calcium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of calcium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.") +AnnotationAssertion( "rph") +AnnotationAssertion( "2017-02-07T13:20:48Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of calcium ion efflux from cell") +AnnotationAssertion( "negative regulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1905913") +AnnotationAssertion(rdfs:label "negative regulation of calcium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of calcium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.") +AnnotationAssertion( "rph") +AnnotationAssertion( "2017-02-07T13:20:56Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium ion efflux from cell") +AnnotationAssertion( "positive regulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion efflux from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1905914") +AnnotationAssertion(rdfs:label "positive regulation of calcium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of acetylcholine biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:20164328") "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process.") @@ -106099,6 +108385,21 @@ AnnotationAssertion( "positive regulation of response to calcium ion") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (negative regulation of calcium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17640527") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2017-02-17T09:42:30Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion import across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1905949") +AnnotationAssertion(rdfs:comment "An example of this is PPP3CA in human (Q08209) in PMID:17640527 (inferred from direct assay).") +AnnotationAssertion(rdfs:label "negative regulation of calcium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of lipid localization) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17564681") "Any process that modulates the frequency, rate or extent of lipid localization.") @@ -106212,6 +108513,43 @@ AnnotationAssertion(rdfs:label "comp EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (calcium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:2145281") "The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-02-07T13:01:29Z") +AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:2145281") "calcium ion efflux from cell") +AnnotationAssertion( "calcium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990034") +AnnotationAssertion(rdfs:label "calcium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (anterograde neuronal dense core vesicle transport) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.") +AnnotationAssertion( "anterograde dense core granule trafficking") +AnnotationAssertion( "anterograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990048") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anterograde neuronal dense core vesicle transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (retrograde neuronal dense core vesicle transport) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") Annotation( "PMID:24762653") "The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:31:44Z") +AnnotationAssertion( "retrograde dense core granule trafficking") +AnnotationAssertion( "retrograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990049") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "retrograde neuronal dense core vesicle transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (lens fiber cell apoptotic process) AnnotationAssertion(Annotation( "CL:0011004") Annotation( "GOC:hjd") Annotation( "PMID:11095619") "Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.") @@ -106360,6 +108698,30 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (dense core granule maturation) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:22654674") "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-09-30T20:35:11Z") +AnnotationAssertion( "dense core vesicle maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990502") +AnnotationAssertion(rdfs:label "dense core granule maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cytoplasmic translational termination) + +AnnotationAssertion(Annotation( "PMID:11570975") "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-12-10T15:48:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990580") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic translational termination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (sebum secreting cell proliferation) AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "PMID:16901790") Annotation( "PMID:18474083") "The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.") @@ -109411,6 +111773,36 @@ AnnotationAssertion( "positive regulation of mesenchymal stem cell differentiation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cytoplasmic translation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2011-06-20T10:39:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000765") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2011-06-20T10:39:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000766") +AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2011-06-20T10:39:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000767") +AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of nephron tubule epithelial cell differentiation) AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.") @@ -189612,6 +192004,29 @@ AnnotationAssertion( "olfactory bulb glomerular layer") SubClassOf( ) +# Class: (olfactory bulb granule cell layer) + +AnnotationAssertion(Annotation( "BTO:0001327") "The granule cell layer contains multiple small round neurons that lack axons. Long dendritic processes of the neurons reach the more superficial layers and inhibit mitral cells and tufted cells. Small distal processes make contacts with the exiting mitral cell axons.") +AnnotationAssertion(Annotation( "BTO:0001327") "granule cell layer") +AnnotationAssertion( "BAMS:MOBgr") +AnnotationAssertion( "BTO:0001327") +AnnotationAssertion( "DMBA:15909") +AnnotationAssertion( "EMAPA:35609") +AnnotationAssertion( "MA:0000971") +AnnotationAssertion( "MBA:220") +AnnotationAssertion( "NLXANAT:20090404") +AnnotationAssertion( "neuronames:2714") +AnnotationAssertion(Annotation( "NLXANAT:20090404") "olfactory bulb main granule cell layer") +AnnotationAssertion( "uberon") +AnnotationAssertion(Annotation( "BAMS:gr") "accessory olfactory bulb granule cell layer") +AnnotationAssertion(Annotation( "NLXANAT:20090404") "granule layer of main olfactory bulb") +AnnotationAssertion(Annotation( "BAMS:MOBgr") Annotation( "BAMS:gr") "main olfactory bulb granule cell layer") +AnnotationAssertion(Annotation( "BAMS:MOBgr") "main olfactory bulb, granule layer") +AnnotationAssertion( "UBERON:0005378") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "olfactory bulb granule cell layer") +SubClassOf( ) + # Class: (dentate gyrus granule cell layer) AnnotationAssertion(Annotation( "BIRNLEX:4129") "Granule cell layer is also called the DG principal cell layer. This one of the three layers of dentate gyrus that lies deep to the molecular layer and is made of densely packed layer that is four to eight granule cells thick.") @@ -222167,6 +224582,7 @@ SubClassOf(ObjectSomeValuesFrom( ) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -222187,7 +224603,6 @@ SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(Annotation( "true"^^xsd:boolean) ObjectPropertyChain( ) ) -SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ObjectInverseOf()) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) diff --git a/src/patterns/definitions.owl b/src/patterns/definitions.owl index 5c99c468e..c9a38d90b 100644 --- a/src/patterns/definitions.owl +++ b/src/patterns/definitions.owl @@ -7,8 +7,8 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-07-19") + +Annotation(owl:versionInfo "2023-08-23")