Tanycyte like cells

[dosumis]

Based on:

https://www.nature.com/articles/s41586-023-06812-z

I think it is reasonable to add the following subclasses of ependymal cell:

• tanycyte-like cell of subfornical organ
• tanycyte-like cell of vascular organ of lamina terminalis
• tanycyte-like cell of area postrema
• tancyte-like cell of subcommissural organ

We could potentially add mouse markers for these from the single cell data.

It looks like we have all except one of these structures in Uberon

The missing one (perhaps we just need a synonym?) is in BTO

[dosumis]

Once these are added - they should be updated in https://github.com/brain-bican/whole_mouse_brain_taxonomy

[dosumis]

Alternatively, we could broaden the definition of tanycyte in CL to cover these. This would be consistent with the structure of the WMB taxonomy

322 is mapped to Tanycyte. CLusters under it include those mapped to type 1 and type 2 tanycytes as well as to the various cell types described as tanycyte-like in the text.

[dosumis]

Related brain-bican/whole_mouse_brain_taxonomy#4

[dosumis]

Note - based on the current def - the term "tanycyte" is used more broadly

"A specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. A tanycyte is found in the adult brain, specifically in the third ventricle, cerebral aqueduct, spinal canal, and floor of the fourth ventricle."

Also how does this relate to the anatomy on the subclasses

"A tanycyte cell found in the ventromedial and dorsomedial nuclei of the hypothalamus". - ie. which ventricle does this correspond to?