Merge pull request #2118 from obophenotype/2117-edit-lung_neuroendocr…

…ine_cell

Addresses #2117 Edit 'lung neuroendocrine cell' (CL edits)

src/ontology/cl-edit.owl

@@ -3007,9 +3007,11 @@ Declaration(Class(obo:CP_0000039))
 Declaration(Class(obo:CP_0000040))
 Declaration(Class(obo:CP_0000043))
 Declaration(Class(obo:D96882F1-8709-49AB-BCA9-772A67EA6C33))
+Declaration(Class(obo:GO_0031045))
 Declaration(Class(obo:GO_0042599))
 Declaration(Class(obo:GO_0044316))
 Declaration(Class(obo:GO_0070278))
+Declaration(Class(obo:GO_0070483))
 Declaration(Class(obo:NCBITaxon_4896))
 Declaration(Class(obo:NCBITaxon_6157))
 Declaration(Class(obo:NCBITaxon_6237))
@@ -24979,8 +24981,15 @@ EquivalentClasses(obo:CL_1000222 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeV
 
 # Class: obo:CL_1000223 (lung neuroendocrine cell)
 
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") Annotation(oboInOwl:hasDbXref "doi:10.3109/01902148209069653") Annotation(oboInOwl:hasDbXref "doi:10.7554/eLife.78216") obo:IAO_0000115 obo:CL_1000223 "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") oboInOwl:hasExactSynonym obo:CL_1000223 "pulmonary neuroendocrine cell")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") Annotation(oboInOwl:hasSynonymType <http://purl.obolibrary.org/obo/cl#abbreviation>) oboInOwl:hasRelatedSynonym obo:CL_1000223 "PNEC")
 AnnotationAssertion(rdfs:label obo:CL_1000223 "lung neuroendocrine cell")
 EquivalentClasses(obo:CL_1000223 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))
+SubClassOf(obo:CL_1000223 obo:CL_0000206)
+SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031045))
+SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001820))
+SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070483))
 
 # Class: obo:CL_1000236 (posterior lateral line nerve glial cell)