diff --git a/src/mappings/fbbt.sssom.tsv b/src/mappings/fbbt.sssom.tsv
index e344406a5..339f29651 100644
--- a/src/mappings/fbbt.sssom.tsv
+++ b/src/mappings/fbbt.sssom.tsv
@@ -10,7 +10,7 @@
 #license: "https://creativecommons.org/licenses/by/4.0/"
 #subject_source: "obo:fbbt.owl"
 #object_source: "obo:cl.owl"
-#mapping_date: "2024-04-24"
+#mapping_date: "2024-05-31"
 subject_id	subject_label	predicate_id	object_id	mapping_justification
 FBbt:00000092	primordial germ cell	semapv:crossSpeciesExactMatch	CL:0000301	semapv:ManualMappingCuration
 FBbt:00000124	epithelial cell	semapv:crossSpeciesExactMatch	CL:0000066	semapv:ManualMappingCuration
diff --git a/src/mappings/zfa.sssom.tsv b/src/mappings/zfa.sssom.tsv
index 932d1b132..6c8f79183 100644
--- a/src/mappings/zfa.sssom.tsv
+++ b/src/mappings/zfa.sssom.tsv
@@ -3,6 +3,7 @@
 #  ZFA: "http://purl.obolibrary.org/obo/ZFA_"
 #mapping_set_id: "http://purl.obolibrary.org/obo/zfa/zfa.sssom.tsv"
 #license: "https://creativecommons.org/licenses/by/3.0/"
+#subject_source: "http://purl.obolibrary.org/obo/zfa.owl"
 subject_id	subject_label	predicate_id	object_id	mapping_justification	mapping_cardinality
 ZFA:0000003	adaxial cell	semapv:crossSpeciesExactMatch	CL:0007016	semapv:UnspecifiedMatching	1:1
 ZFA:0000084	yolk	semapv:crossSpeciesExactMatch	CL:0000428	semapv:UnspecifiedMatching	1:1
diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl
index 2a1996125..5271945d7 100644
--- a/src/ontology/cl-edit.owl
+++ b/src/ontology/cl-edit.owl
@@ -3137,6 +3137,8 @@ Declaration(Class(obo:UBERON_0003677))
 Declaration(Class(obo:UBERON_0003718))
 Declaration(Class(obo:UBERON_0004024))
 Declaration(Class(obo:UBERON_0004026))
+Declaration(Class(obo:UBERON_0004196))
+Declaration(Class(obo:UBERON_0004197))
 Declaration(Class(obo:UBERON_0005101))
 Declaration(Class(obo:UBERON_0005102))
 Declaration(Class(obo:UBERON_0005378))
@@ -3253,7 +3255,7 @@ AnnotationAssertion(rdfs:label obo:IAO_0000115 "definition")
 
 AnnotationAssertion(rdfs:label obo:IAO_0000424 "expand expression to")
 
-# Annotation Property: obo:IAO_0000700 (has ontology root term)
+# Annotation Property: obo:IAO_0000700 (preferred_root)
 
 AnnotationAssertion(rdfs:label obo:IAO_0000700 "preferred_root")
 
@@ -3347,11 +3349,11 @@ AnnotationAssertion(rdfs:label oboInOwl:hasBroadSynonym "has_broad_synonym")
 
 AnnotationAssertion(rdfs:label oboInOwl:hasDbXref "database_cross_reference")
 
-# Annotation Property: oboInOwl:hasExactSynonym (has exact synonym)
+# Annotation Property: oboInOwl:hasExactSynonym (has_exact_synonym)
 
 AnnotationAssertion(rdfs:label oboInOwl:hasExactSynonym "has_exact_synonym")
 
-# Annotation Property: oboInOwl:hasNarrowSynonym (has narrow synonym)
+# Annotation Property: oboInOwl:hasNarrowSynonym (has_narrow_synonym)
 
 AnnotationAssertion(rdfs:label oboInOwl:hasNarrowSynonym "has_narrow_synonym")
 
@@ -16897,13 +16899,13 @@ SubClassOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000413
 
 # Class: obo:CL_0002307 (brush border cell of the proximal tubule)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:1-4160-2328-3") obo:IAO_0000115 obo:CL_0002307 "A brush border epithelial cell located in the proximal tubule of the kidney that detects fluid flow.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:1-4160-2328-3") Annotation(oboInOwl:hasDbXref "PMID:23799132") obo:IAO_0000115 obo:CL_0002307 "A brush border epithelial cell located in the proximal tubule of the kidney, essential for reabsorbing substances like glucose and amino acids from the glomerular filtrate. These cells also secrete organic ions, playing a crucial role in maintaining kidney homeostasis, including electrolyte and acid-base balance, and excreting metabolic waste.")
 AnnotationAssertion(terms:contributor obo:CL_0002307 <https://orcid.org/0000-0003-1980-3228>)
 AnnotationAssertion(oboInOwl:creation_date obo:CL_0002307 "2010-09-14T11:29:20Z"^^xsd:dateTime)
 AnnotationAssertion(rdfs:comment obo:CL_0002307 "The vast majority of proximal tubule epithelial cells have a brush border, but there are rare exceptions.")
 AnnotationAssertion(rdfs:label obo:CL_0002307 "brush border cell of the proximal tubule")
+EquivalentClasses(obo:CL_0002307 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
 SubClassOf(obo:CL_0002307 obo:CL_0002306)
-SubClassOf(obo:CL_0002307 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903))
 
 # Class: obo:CL_0002308 (epithelial cell of skin gland)
 
@@ -27034,10 +27036,9 @@ SubClassOf(obo:CL_1000804 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000521
 
 AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000838 "KUPO:0001045")
 AnnotationAssertion(rdfs:label obo:CL_1000838 "kidney proximal convoluted tubule epithelial cell")
-EquivalentClasses(obo:CL_1000838 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001287)))
+EquivalentClasses(obo:CL_1000838 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001287) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000838 obo:CL_0002306)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000838 obo:CL_1000615)
-SubClassOf(obo:CL_1000838 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001287))
 
 # Class: obo:CL_1000839 (kidney proximal straight tubule epithelial cell)
 
@@ -27047,7 +27048,6 @@ EquivalentClasses(obo:CL_1000839 ObjectIntersectionOf(obo:CL_0002306 ObjectSomeV
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000839 obo:CL_0002306)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000839 obo:CL_1000615)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000839 obo:CL_1000616)
-SubClassOf(obo:CL_1000839 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001290))
 
 # Class: obo:CL_1000849 (kidney distal convoluted tubule epithelial cell)
 
@@ -30679,26 +30679,30 @@ SubClassOf(obo:CL_4030008 obo:CL_0000653)
 
 # Class: obo:CL_4030009 (epithelial cell of proximal tubule segment 1)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030009 "A brush border cell that is part of segment 1 (S1) of the proximal tubule epithelium.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23799132") Annotation(oboInOwl:hasDbXref "PMID:23897681") Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030009 "A brush border cell that is part of segment 1 (S1) of the proximal tubule epithelium, located in the renal cortex.")
 AnnotationAssertion(terms:date obo:CL_4030009 "2022-05-10T13:14:00Z"^^xsd:dateTime)
 AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030009 "epithelial cell of segment 1 of proximal tubule")
 AnnotationAssertion(rdfs:label obo:CL_4030009 "epithelial cell of proximal tubule segment 1")
+EquivalentClasses(obo:CL_4030009 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004196) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
 SubClassOf(obo:CL_4030009 obo:CL_0002307)
 
 # Class: obo:CL_4030010 (epithelial cell of proximal tubule segment 2)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030010 "A brush border cell that is part of segment 2 (S2) of the proximal tubule epithelium.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23799132") Annotation(oboInOwl:hasDbXref "PMID:23897681") Annotation(oboInOwl:hasDbXref "PMID:31249312") Annotation(oboInOwl:hasDbXref "PMID:31253652") obo:IAO_0000115 obo:CL_4030010 "A brush border cell that is part of segment 2 (S2) of the proximal tubule epithelium, located in the renal cortex. In addition to its reabsorptive functions, it is also specialized in the secretion of organic anions and cations, including para-aminohippurate.")
 AnnotationAssertion(terms:date obo:CL_4030010 "2022-05-10T13:26:13Z"^^xsd:dateTime)
 AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030010 "epithelial cell of segment 2 of proximal tubule")
 AnnotationAssertion(rdfs:label obo:CL_4030010 "epithelial cell of proximal tubule segment 2")
+EquivalentClasses(obo:CL_4030010 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004197) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
 SubClassOf(obo:CL_4030010 obo:CL_0002307)
 
 # Class: obo:CL_4030011 (epithelial cell of proximal tubule segment 3)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030011 "A brush border cell that is part of segment 3 (S3) of the proximal tubule epithelium.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:23799132") Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030011 "A brush border cell that is part of segment 3 (S3) of the proximal tubule epithelium, which extends from the medullary rays of the renal cortex into the outer medulla.")
 AnnotationAssertion(terms:date obo:CL_4030011 "2022-05-10T13:31:06Z"^^xsd:dateTime)
 AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030011 "epithelial cell of segment 3 of proximal tubule")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") rdfs:comment obo:CL_4030011 "The epithelial cell of proximal tubule segment 3 operates under relatively hypoxic conditions and is particularly susceptible to ischemic injury.")
 AnnotationAssertion(rdfs:label obo:CL_4030011 "epithelial cell of proximal tubule segment 3")
+EquivalentClasses(obo:CL_4030011 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001290) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005903)))
 SubClassOf(obo:CL_4030011 obo:CL_0002307)
 
 # Class: obo:CL_4030012 (kidney loop of Henle short descending thin limb epithelial cell)
diff --git a/src/ontology/components/cellxgene_subset.owl b/src/ontology/components/cellxgene_subset.owl
index 0eab455e3..7966e3926 100644
--- a/src/ontology/components/cellxgene_subset.owl
+++ b/src/ontology/components/cellxgene_subset.owl
@@ -7,8 +7,8 @@ Prefix(rdfs:=<http://www.w3.org/2000/01/rdf-schema#>)
 
 
 Ontology(<http://purl.obolibrary.org/obo/cl/components/cellxgene_subset.owl>
-<http://purl.obolibrary.org/obo/cl/releases/2024-05-15/components/cellxgene_subset.owl>
-Annotation(owl:versionInfo "2024-05-15")
+<http://purl.obolibrary.org/obo/cl/releases/2024-06-13/components/cellxgene_subset.owl>
+Annotation(owl:versionInfo "2024-06-13")
 
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000000>))
 Declaration(Class(<http://purl.obolibrary.org/obo/CL_0000001>))
diff --git a/src/ontology/components/mappings.owl b/src/ontology/components/mappings.owl
index 56e87ec7d..cfb6e4cbc 100644
--- a/src/ontology/components/mappings.owl
+++ b/src/ontology/components/mappings.owl
@@ -4572,5 +4572,5 @@
 
 
 
-<!-- Generated by the OWL API (version 4.5.26) https://github.com/owlcs/owlapi -->
+<!-- Generated by the OWL API (version 4.5.29) https://github.com/owlcs/owlapi -->
 
diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl
index cbdcb2055..60fd117e7 100644
--- a/src/ontology/imports/merged_import.owl
+++ b/src/ontology/imports/merged_import.owl
@@ -7,8 +7,8 @@ Prefix(rdfs:=<http://www.w3.org/2000/01/rdf-schema#>)
 
 
 Ontology(<http://purl.obolibrary.org/obo/cl/imports/merged_import.owl>
-<http://purl.obolibrary.org/obo/cl/releases/2024-06-04/imports/merged_import.owl>
-Annotation(owl:versionInfo "2024-06-04")
+<http://purl.obolibrary.org/obo/cl/releases/2024-06-13/imports/merged_import.owl>
+Annotation(owl:versionInfo "2024-06-13")
 
 Declaration(Class(<http://purl.obolibrary.org/obo/BFO_0000002>))
 Declaration(Class(<http://purl.obolibrary.org/obo/BFO_0000003>))
@@ -5764,6 +5764,8 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072027>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072028>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072029>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072030>))
+Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072031>))
+Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072032>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072033>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072036>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072037>))
@@ -5891,6 +5893,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072225>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072227>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072229>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072230>))
+Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072231>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072233>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072234>))
 Declaration(Class(<http://purl.obolibrary.org/obo/GO_0072235>))
@@ -10811,6 +10814,8 @@ Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004190>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004193>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004194>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004195>))
+Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004196>))
+Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004197>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004198>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004199>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0004200>))
@@ -11291,6 +11296,7 @@ Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005120>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005122>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005124>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005125>))
+Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005126>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005127>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005129>))
 Declaration(Class(<http://purl.obolibrary.org/obo/UBERON_0005130>))
@@ -14056,6 +14062,7 @@ Declaration(AnnotationProperty(<http://purl.org/dc/elements/1.1/title>))
 Declaration(AnnotationProperty(<http://purl.org/dc/terms/contributor>))
 Declaration(AnnotationProperty(<http://purl.org/dc/terms/date>))
 Declaration(AnnotationProperty(<http://purl.org/dc/terms/license>))
+Declaration(AnnotationProperty(<http://purl.org/dc/terms/title>))
 Declaration(AnnotationProperty(<http://www.geneontology.org/formats/oboInOwl#SubsetProperty>))
 Declaration(AnnotationProperty(<http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty>))
 Declaration(AnnotationProperty(<http://www.geneontology.org/formats/oboInOwl#consider>))
@@ -80250,6 +80257,32 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0072030> "shor
 EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0072030> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0048856> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002296> <http://purl.obolibrary.org/obo/UBERON_0004195>)))
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0072030> <http://purl.obolibrary.org/obo/GO_0072006>)
 
+# Class: <http://purl.obolibrary.org/obo/GO_0072031> (proximal convoluted tubule segment 1 development)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MA:0002612") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0072031> "The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0072031> "mah")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0072031> "2010-01-25T02:55:57Z")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0072031> "S1 development")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0072031> "biological_process")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0072031> "GO:0072031")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0072031> "proximal convoluted tubule segment 1 development")
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0072031> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0048856> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002296> <http://purl.obolibrary.org/obo/UBERON_0004196>)))
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0072031> <http://purl.obolibrary.org/obo/GO_0048856>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0072031> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0072019>))
+
+# Class: <http://purl.obolibrary.org/obo/GO_0072032> (proximal convoluted tubule segment 2 development)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MA:0002613") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0072032> "The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0072032> "mah")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0072032> "2010-01-25T02:56:36Z")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0072032> "S2 development")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0072032> "biological_process")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0072032> "GO:0072032")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0072032> "proximal convoluted tubule segment 2 development")
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0072032> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0048856> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002296> <http://purl.obolibrary.org/obo/UBERON_0004197>)))
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0072032> <http://purl.obolibrary.org/obo/GO_0048856>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0072032> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0072019>))
+
 # Class: <http://purl.obolibrary.org/obo/GO_0072033> (renal vesicle formation)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0072033> "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.")
@@ -81789,6 +81822,19 @@ EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0072230> ObjectIntersection
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0072230> <http://purl.obolibrary.org/obo/GO_0072020>)
 SubClassOf(<http://purl.obolibrary.org/obo/GO_0072230> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0072237>))
 
+# Class: <http://purl.obolibrary.org/obo/GO_0072231> (metanephric proximal convoluted tubule segment 1 development)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:bf") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0072231> "The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#created_by> <http://purl.obolibrary.org/obo/GO_0072231> "mah")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#creation_date> <http://purl.obolibrary.org/obo/GO_0072231> "2010-03-18T03:39:10Z")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/GO_0072231> "metanephric S1 development")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/GO_0072231> "biological_process")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/GO_0072231> "GO:0072231")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/GO_0072231> "metanephric proximal convoluted tubule segment 1 development")
+EquivalentClasses(<http://purl.obolibrary.org/obo/GO_0072231> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/GO_0048856> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002296> <http://purl.obolibrary.org/obo/UBERON_0005126>)))
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0072231> <http://purl.obolibrary.org/obo/GO_0072031>)
+SubClassOf(<http://purl.obolibrary.org/obo/GO_0072231> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/GO_0072229>))
+
 # Class: <http://purl.obolibrary.org/obo/GO_0072233> (metanephric thick ascending limb development)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GOC:mtg_kidney_jan10") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/GO_0072233> "The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.")
@@ -178946,6 +178992,48 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004195> "short nephron")
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004195> <http://purl.obolibrary.org/obo/UBERON_0001285>)
 
+# Class: <http://purl.obolibrary.org/obo/UBERON_0004196> (proximal convoluted tubule segment 1)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072031") Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "http://sourceforge.net/tracker/?func=detail&atid=440764&aid=3298740&group_id=36855") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004196> "The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO].")
+AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0004196> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/UBERON_0004196> "UBERON:0006432")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072031") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/UBERON_0004196> "S1")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004196> "EMAPA:29657")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004196> "MA:0002612")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004196> "S1 portion of renal tubule")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004196> "S1 portion of tubule")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MA:0002612") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004196> "proximal tubule segment 1")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EMAPA:29657") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004196> "segment 1 of proximal tubule")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0004196> "uberon")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0004196> "UBERON:0004196")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0004196> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004196> "proximal convoluted tubule segment 1")
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004196> <http://purl.obolibrary.org/obo/UBERON_0004120>)
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004196> <http://purl.obolibrary.org/obo/UBERON_0006555>)
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "GO") <http://purl.obolibrary.org/obo/UBERON_0004196> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0001287>))
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "GO") <http://purl.obolibrary.org/obo/UBERON_0004196> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002216> <http://purl.obolibrary.org/obo/GO_0070295>))
+
+# Class: <http://purl.obolibrary.org/obo/UBERON_0004197> (proximal convoluted tubule segment 2)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072032") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004197> "The S2 portion of the tubule is involved in reabsorption of water and sodium chloride[GO].")
+AnnotationAssertion(<http://purl.obolibrary.org/obo/RO_0002175> <http://purl.obolibrary.org/obo/UBERON_0004197> <http://purl.obolibrary.org/obo/NCBITaxon_9606>)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasAlternativeId> <http://purl.obolibrary.org/obo/UBERON_0004197> "UBERON:0006433")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072032") <http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym> <http://purl.obolibrary.org/obo/UBERON_0004197> "S2")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004197> "EMAPA:29659")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/UBERON_0004197> "MA:0002613")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004197> "S2 portion of renal tubule")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004197> "S2 portion of tubule")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "MA:0002613") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004197> "proximal tubule segment 2")
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "EMAPA:29659") <http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/UBERON_0004197> "segment 2 of proximal tubule")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0004197> "uberon")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0004197> "UBERON:0004197")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/UBERON_0004197> <http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas>)
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0004197> "proximal convoluted tubule segment 2")
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004197> <http://purl.obolibrary.org/obo/UBERON_0004120>)
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0004197> <http://purl.obolibrary.org/obo/UBERON_0006555>)
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "GO") <http://purl.obolibrary.org/obo/UBERON_0004197> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0001287>))
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "GO") <http://purl.obolibrary.org/obo/UBERON_0004197> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002216> <http://purl.obolibrary.org/obo/GO_0070295>))
+
 # Class: <http://purl.obolibrary.org/obo/UBERON_0004198> (comma-shaped body)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072049") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0004198> "The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.")
@@ -188749,6 +188837,16 @@ SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0005125> <http://purl.obolibra
 SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0005125> <http://purl.obolibrary.org/obo/UBERON_0005146>)
 SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#is_inferred> "true") Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships") <http://purl.obolibrary.org/obo/UBERON_0005125> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0005151>))
 
+# Class: <http://purl.obolibrary.org/obo/UBERON_0005126> (metanephric S1)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072231") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0005126> "The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO].")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/UBERON_0005126> "uberon")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/UBERON_0005126> "UBERON:0005126")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/UBERON_0005126> "metanephric S1")
+EquivalentClasses(<http://purl.obolibrary.org/obo/UBERON_0005126> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/UBERON_0004196> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000081>)))
+SubClassOf(<http://purl.obolibrary.org/obo/UBERON_0005126> <http://purl.obolibrary.org/obo/UBERON_0004196>)
+SubClassOf(Annotation(<http://www.geneontology.org/formats/oboInOwl#is_inferred> "true") Annotation(<http://www.geneontology.org/formats/oboInOwl#source> "https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships") <http://purl.obolibrary.org/obo/UBERON_0005126> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0005124>))
+
 # Class: <http://purl.obolibrary.org/obo/UBERON_0005127> (metanephric thick ascending limb)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0072233") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/UBERON_0005127> "At the macula densa, the thick ascending limb connects to the distal convoluted tubule[GO].")
diff --git a/src/patterns/definitions.owl b/src/patterns/definitions.owl
index 046777e53..ed7abf2cf 100644
--- a/src/patterns/definitions.owl
+++ b/src/patterns/definitions.owl
@@ -7,8 +7,8 @@ Prefix(rdfs:=<http://www.w3.org/2000/01/rdf-schema#>)
 
 
 Ontology(<http://purl.obolibrary.org/obo/cl/patterns/definitions.owl>
-<http://purl.obolibrary.org/obo/cl/releases/2024-02-13/patterns/definitions.owl>
-Annotation(owl:versionInfo "2024-02-13")
+<http://purl.obolibrary.org/obo/cl/releases/2024-06-13/patterns/definitions.owl>
+Annotation(owl:versionInfo "2024-06-13")