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Possible bug with projectionDriver() when normalize_pattern = T. #28

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jaredslosberg opened this issue Jul 10, 2023 · 2 comments
Open

Possible bug with projectionDriver() when normalize_pattern = T. #28

jaredslosberg opened this issue Jul 10, 2023 · 2 comments

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@jaredslosberg
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Check that group means and variances are appropriately adjusted by pattern normalization. Different numbers of genes are returned as significant when normalize_pattern is False.
@jaredslosberg
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Further, function should be rewritten so that the test returns the pvalue. As is, the threshold is user provided and used to construct the confidence interval for difference in group means, and just returns whether or not a gene is significant at that threshold.

@jaredslosberg
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@rpalaganas

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@jaredslosberg