diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 81ea1b2..17f54c2 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -102,3 +102,28 @@ jobs:
         run: |
           cd build
           make test
+
+  # NOTE: The pip-installed version of libsupermesh does not include any tests, so only check
+  # that it builds.
+  build_pip:
+    name: "Build libsupermesh with pip"
+    # The type of runner that the job will run on
+    runs-on: self-hosted
+    # The docker container to use.
+    container:
+      image: firedrakeproject/firedrake-env:latest
+
+    steps:
+      - uses: actions/checkout@v4
+
+      - uses: actions/setup-python@v4
+        with:
+          python-version: '3.11'
+
+      - name: Install libsupermesh
+        shell: bash
+        run: |
+          python -m venv ../test_env
+          source ../test_env/bin/activate
+          export MPI_HOME=$MPICH_DIR
+          pip install .
diff --git a/AUTHORS b/AUTHORS
index ade4ac3..8fecedf 100644
--- a/AUTHORS
+++ b/AUTHORS
@@ -6,3 +6,4 @@ Contributors to libsupermesh:
 * Dr. Patrick E. Farrell, Mathematical Institute, University of Oxford, UK,
   and Center for Biomedical Computing, Simula Research Laboratory, Oslo, Norway
 * Mr. Matteo Croci, Mathematical Institute, University of Oxford, UK
+* Dr. Jack Betteridge, Department of Mathematics, Imperial College London, UK
diff --git a/CMakeLists.txt b/CMakeLists.txt
index fc62c53..21af648 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -42,7 +42,11 @@ set(CMAKE_Fortran_MODULE_DIRECTORY ${LIBSUPERMESH_BINARY_DIR}/include)
 include_directories(${LIBSUPERMESH_SOURCE_DIR}/include)
 include_directories(${LIBSUPERMESH_BINARY_DIR}/include)
 include_directories(${LIBSUPERMESH_BINARY_DIR}/include_local)
-option(BUILD_SHARED_LIBS "Build shared libraries" OFF)
+if("${SKBUILD}" STREQUAL 2)
+  option(BUILD_SHARED_LIBS "Build shared libraries" ON)
+else()
+  option(BUILD_SHARED_LIBS "Build shared libraries" OFF)
+endif()
 
 find_package(MPI REQUIRED)
 set(link_libraries ${MPI_Fortran_LIBRARIES})
@@ -127,7 +131,7 @@ message(STATUS "")
 
 # Python is not required, but we want to add pip packages to spatialindex search path
 set(Python_FIND_VIRTUALENV "FIRST")
-find_package(Python)
+find_package(Python COMPONENTS Interpreter Development.Module)
 if(Python_FOUND)
     message(STATUS "Python_VERSION_MAJOR " ${Python_VERSION_MAJOR})
     message(STATUS "Python_VERSION_MINOR " ${Python_VERSION_MINOR})
@@ -152,6 +156,11 @@ if((NOT spatialindexlib) AND (Python_FOUND))
     # Forces build to fail if we still cannot find spatialindex
     unset(spatialindexlib)
     find_library(spatialindexlib NAMES spatialindex REQUIRED)
+  else()
+    # Get the headers
+    execute_process(COMMAND ${Python_EXECUTABLE} -c "import rtree; print(rtree.finder.get_include(), end='')"
+                  OUTPUT_VARIABLE spatialindexheaders
+                  )
   endif()
 endif()
 
@@ -176,7 +185,7 @@ endif()
 find_path(spatialindexheaders
           NAMES spatialindex/SpatialIndex.h
           REQUIRED
-          PATHS /usr/local/include /usr/include $ENV{VIRTUAL_ENV}/lib/python${Python_VERSION_MAJOR}.${Python_VERSION_MINOR}/site-packages/rtree/include
+          PATHS /usr/local/include /usr/include $ENV{VIRTUAL_ENV}/lib/python${Python_VERSION_MAJOR}.${Python_VERSION_MINOR}/site-packages/rtree/include spatialindexheaders
           )
 if(spatialindexheaders)
   message(STATUS "Found libspatialindex headers: " ${spatialindexheaders})
@@ -184,35 +193,57 @@ if(spatialindexheaders)
 endif()
 
 file(GLOB source_files ${LIBSUPERMESH_SOURCE_DIR}/src/*.F90 ${LIBSUPERMESH_SOURCE_DIR}/src/*.c ${LIBSUPERMESH_SOURCE_DIR}/src/*.cpp)
-add_library(supermesh ${source_files})
+if("${SKBUILD}" STREQUAL 2)
+  python_add_library(supermesh MODULE WITH_SOABI ${source_files})
+else()
+  add_library(supermesh ${source_files})
+endif()
 
-set(test_main ${LIBSUPERMESH_SOURCE_DIR}/src/tests/test_main.cpp)
-file(GLOB unittest_files ${LIBSUPERMESH_SOURCE_DIR}/src/tests/*.F90)
-set(unittests "")
-foreach(unittest_file ${unittest_files})
-  get_filename_component(unittest ${unittest_file} NAME_WE)
-  add_executable(${unittest} ${unittest_file} ${test_main})
-  list(APPEND unittests ${unittest})
-  set_property(TARGET ${unittest} PROPERTY COMPILE_DEFINITIONS "TESTNAME=${unittest}")
-  if(unittest MATCHES parallel)
-    add_test(${unittest} ${MPIEXEC_EXECUTABLE} ${MPIEXEC_NUMPROC_FLAG} 4 ${MPIEXEC_PREFLAGS} ./${unittest} ${MPIEXEC_POSTFLAGS})
-  else()
-    add_test(${unittest} ${unittest})
-  endif()
-  set_tests_properties(${unittest} PROPERTIES FAIL_REGULAR_EXPRESSION "Fail:")
-endforeach()
+target_link_libraries(supermesh PUBLIC ${link_libraries})
+set_target_properties(supermesh PROPERTIES INSTALL_RPATH "$ORIGIN/../Rtree.libs")
+set_target_properties(supermesh PROPERTIES LINK_FLAGS "${MPI_Fortran_LINK_FLAGS}")
+if("${SKBUILD}" STREQUAL 2)
+  # use, i.e. don't skip the full RPATH for the build tree
+  set(CMAKE_SKIP_BUILD_RPATH FALSE)
 
-set(test_link_libraries supermesh ${link_libraries} ${MPI_CXX_LIBRARIES})
-target_link_libraries(supermesh ${link_libraries})
-set_target_properties(supermesh PROPERTIES INSTALL_RPATH_USE_LINK_PATH TRUE)
-foreach(test ${unittests})
-  target_link_libraries(${test} ${test_link_libraries})
-endforeach()
+  # when building, don't use the install RPATH already
+  # (but later on when installing)
+  set(CMAKE_BUILD_WITH_INSTALL_RPATH FALSE)
 
-set_target_properties(supermesh PROPERTIES LINK_FLAGS "${MPI_Fortran_LINK_FLAGS}")
-foreach(unittest ${unittests})
-  set_target_properties(${unittest} PROPERTIES LINK_FLAGS "${MPI_Fortran_LINK_FLAGS} ${MPI_CXX_LINK_FLAGS}")
-endforeach()
+  set(CMAKE_INSTALL_RPATH "${CMAKE_INSTALL_PREFIX}/lib")
+
+  # add the automatically determined parts of the RPATH
+  # which point to directories outside the build tree to the install RPATH
+  set(CMAKE_INSTALL_RPATH_USE_LINK_PATH TRUE)
+endif()
+
+# Only build tests if not built by scikit-build-core
+if(NOT "${SKBUILD}" STREQUAL 2)
+  set(test_main ${LIBSUPERMESH_SOURCE_DIR}/src/tests/test_main.cpp)
+  file(GLOB unittest_files ${LIBSUPERMESH_SOURCE_DIR}/src/tests/*.F90)
+  set(unittests "")
+  foreach(unittest_file ${unittest_files})
+    get_filename_component(unittest ${unittest_file} NAME_WE)
+    add_executable(${unittest} ${unittest_file} ${test_main})
+    list(APPEND unittests ${unittest})
+    set_property(TARGET ${unittest} PROPERTY COMPILE_DEFINITIONS "TESTNAME=${unittest}")
+    if(unittest MATCHES parallel)
+      add_test(${unittest} ${MPIEXEC_EXECUTABLE} ${MPIEXEC_NUMPROC_FLAG} 4 ${MPIEXEC_PREFLAGS} ./${unittest} ${MPIEXEC_POSTFLAGS})
+    else()
+      add_test(${unittest} ${unittest})
+    endif()
+    set_tests_properties(${unittest} PROPERTIES FAIL_REGULAR_EXPRESSION "Fail:")
+  endforeach()
+
+  set(test_link_libraries supermesh ${link_libraries} ${MPI_CXX_LIBRARIES})
+  foreach(test ${unittests})
+    target_link_libraries(${test} ${test_link_libraries})
+  endforeach()
+
+  foreach(unittest ${unittests})
+    set_target_properties(${unittest} PROPERTIES LINK_FLAGS "${MPI_Fortran_LINK_FLAGS} ${MPI_CXX_LINK_FLAGS}")
+  endforeach()
+endif()
 
 configure_file (
   "${LIBSUPERMESH_SOURCE_DIR}/config/libsupermesh.pc.in"
@@ -246,9 +277,14 @@ if(ENABLE_DOCS)
     FORCE_PDF EXCLUDE_FROM_ALL BIBFILES doc/bibliography.bib)
 endif()
 
-install(TARGETS supermesh DESTINATION lib)
-install(DIRECTORY ${LIBSUPERMESH_BINARY_DIR}/include DESTINATION ${CMAKE_INSTALL_PREFIX})
-install(FILES ${LIBSUPERMESH_BINARY_DIR}/config/libsupermesh.pc DESTINATION lib/pkgconfig)
+if("${SKBUILD}" STREQUAL 2)
+  install(TARGETS supermesh DESTINATION supermesh)
+  install(DIRECTORY ${LIBSUPERMESH_BINARY_DIR}/include DESTINATION supermesh)
+else()
+  install(TARGETS supermesh DESTINATION lib)
+  install(DIRECTORY ${LIBSUPERMESH_BINARY_DIR}/include DESTINATION ${CMAKE_INSTALL_PREFIX})
+  install(FILES ${LIBSUPERMESH_BINARY_DIR}/config/libsupermesh.pc DESTINATION lib/pkgconfig)
+endif()
 
 file(GLOB data_files ${LIBSUPERMESH_SOURCE_DIR}/src/tests/data/*.ele
                      ${LIBSUPERMESH_SOURCE_DIR}/src/tests/data/*.node)
diff --git a/README.md b/README.md
index dcf15f5..4b5c809 100644
--- a/README.md
+++ b/README.md
@@ -29,3 +29,4 @@ libsupermesh is available under the [GNU Lesser General Public License version 2
 * Dr. Patrick E. Farrell, Mathematical Institute, University of Oxford, UK,
   and Center for Biomedical Computing, Simula Research Laboratory, Oslo, Norway
 * Mr. Matteo Croci, Mathematical Institute, University of Oxford, UK
+* Dr. Jack Betteridge, Department of Mathematics, Imperial College London, UK
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000..c62f317
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,32 @@
+[project]
+name = "libsupermesh"
+version = "1.0.1"
+description = "A parallel supermeshing library"
+readme = "README.md"
+authors = [
+  {name = "James R. Maddison", email = "j.r.maddison@ed.ac.uk"},
+  {name = "Iakovos Panourgias", email = ""},
+  {name = "Patrick E. Farrell", email = ""},
+  {name = "Matteo Croci", email = ""},
+  {name = "Jack Betteridge", email = "J.Betteridge@imperial.ac.uk"},
+]
+maintainers = [
+  {name = "Jack Betteridge", email = "J.Betteridge@imperial.ac.uk"},
+]
+dependencies = [
+  "rtree>=1.2",
+]
+classifiers = [
+  "Development Status :: 5 - Production/Stable",
+  "License :: OSI Approved :: GNU Lesser General Public License v2 or later (LGPLv2+)",
+  "Programming Language :: Python",
+  "Operating System :: OS Independent"
+]
+
+[project.urls]
+Repository = "https://github.com/firedrakeproject/libsupermesh"
+
+[build-system]
+requires = ["scikit-build-core", "rtree>=1.2"]
+build-backend = "scikit_build_core.build"
+