diff --git a/proton b/proton
index b6bb6a79e..e8b36f896 100755
--- a/proton
+++ b/proton
@@ -1461,6 +1461,12 @@ class Session:
         if "PROTON_CRASH_REPORT_DIR" in self.env:
             self.env["WINE_CRASH_REPORT_DIR"] = self.env["PROTON_CRASH_REPORT_DIR"]
 
+        # NVIDIA software may check NVIDIA_WINE_DLL_DIR as a search-path for
+        # driver-provided DLLs for use by Proton/Wine.
+        nvidia_wine_dll_dir = find_nvidia_wine_dll_dir()
+        if nvidia_wine_dll_dir:
+            self.env["NVIDIA_WINE_DLL_DIR"] = nvidia_wine_dll_dir
+
         if "PROTON_LOG" in self.env and nonzero(self.env["PROTON_LOG"]):
             if self.setup_logging(append_forever=False):
                 self.log_file.write("======================\n")