diff --git a/.github/workflows/pypi_publish.yml b/.github/workflows/pypi_publish.yml
new file mode 100755
index 00000000..0e47ef9b
--- /dev/null
+++ b/.github/workflows/pypi_publish.yml
@@ -0,0 +1,49 @@
+name: Publish package python distribution to Pypi
+
+on:
+  release:
+    types: [published]
+  workflow_dispatch:
+
+jobs:
+    build:
+      name: Build distribution
+      runs-on: ubuntu-latest
+      steps:
+      - uses: actions/checkout@v4
+      - name: Set up Python
+        uses: actions/setup-python@v5
+        with:
+          python-version: 3.12.7
+      - name: Install pypi/build
+        run: >-
+          python3 -m
+          pip install
+          build
+          --user
+      - name: Build a binary wheel and a source tarball
+        run: python3 -m build
+      - name: Store the distribution packages
+        uses: actions/upload-artifact@v4
+        with:
+          name: python-package-distributions
+          path: dist/
+
+    publish-to-pypi:
+      name: Publish dist to PyPI
+      needs:
+      - build
+      runs-on: ubuntu-latest
+      environment:
+        name: pypi
+        url: https://pypi.org/p/buisciii-tools
+      permissions:
+        id-token: write
+      steps:
+      - name: Download all the dists
+        uses: actions/download-artifact@v4
+        with:
+          name: python-package-distributions
+          path: dist/
+      - name: Publish to PyPI
+        uses: pypa/gh-action-pypi-publish@release/v1
diff --git a/CHANGELOG.md b/CHANGELOG.md
index b76da9b9..61cf8d30 100755
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,12 +10,16 @@ The format is based on [Keep a Changelog](https://keepachangelog.com/en/1.0.0/),
 
 Code contributions to the new version:
 
+- [Pablo Mata](https://github.com/Shettland)
+
 ### Template fixes and updates
 
 ### Modules
 
 #### Added enhancements
 
+- Included a new github action to automatically publish releases to pypi [#351](https://github.com/BU-ISCIII/buisciii-tools/pull/351)
+
 #### Fixes
 
 #### Changed
diff --git a/README.md b/README.md
index da5522a9..dddebc62 100644
--- a/README.md
+++ b/README.md
@@ -31,7 +31,7 @@ BU-ISCIII provides a serie or services in its portfolio for supporting bioinform
 ```bash
 micromamba create -n buisciii -f environment.yml
 micromamba activate buisciii
-pip install --force-reinstall --upgrade git+https://github.com/bu-isciii/buisciii-tools.git@main
+pip install buisciii-tools
 ```
 
 or
@@ -40,7 +40,7 @@ or
 git checkout main
 conda create -n buisciii -f environment.yml
 conda activate 
-pip install .
+pip install buisciii-tools
 ```
 
 ### Dev version